Abstract
After prolonged adaptation of rats to high-altitude hypoxia (in a pressure chamber at an “altitude” of 6500 m, for 6 h daily for 30–40 days) considerable hyperemia of the intestinal wall and mesentery was observed; the number of functioning capillaries was several times greater than in the control animals but the blood flow in the dilated microvessels was slowed and its structure was disturbed. Besides obvious hemoconcentration in the arteries and veins, hemodilution was observed in the capillaries. Definite hemorheological changes evidently connected with the polycythemia and increased hematocrit index were noted.
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Shtykhno, Y.M., Titova, I.P. Effect of adaptation to high-altitude hypoxia on the microcirculation in the rat mesentery. Bull Exp Biol Med 83, 622–624 (1977). https://doi.org/10.1007/BF00800730
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DOI: https://doi.org/10.1007/BF00800730