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Effect of hyperbaric oxygenation on some functional and morphological properties of the heart and on catecholamine metabolism in compensatory hypertrophy of the myocardium

  • Pathological Physiology and General Pathology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Less-marked hypertrophy and signs of myocardial degeneration developed in rabbits exposed for one month to hyperbaric oxygenation (HBO) after the formation of stenosis of the ascending aorta, and the contractile power of the left ventricle was increased more than in animals with stenosis of the aorta kept under ordinary conditions. In rabbits with hypertrophy of the heart developing under conditions of HBO increased powers of adaptation of the myocardium to physical exertion were accompanied by an increase in the functional reserve of the sympathetic control apparatus. HBO evidently favors the development of optimal adaptation of the heart to an increased pressure load.

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Efuni, S.N., Demurov, E.A., Koloskov, Y.B. et al. Effect of hyperbaric oxygenation on some functional and morphological properties of the heart and on catecholamine metabolism in compensatory hypertrophy of the myocardium. Bull Exp Biol Med 84, 939–943 (1977). https://doi.org/10.1007/BF00798510

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  • DOI: https://doi.org/10.1007/BF00798510

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