Summary
The ability of acute-phase rabbit serums to react with somatic pneumococcal polysaccharide has been confirmed. The complement-fixation test is applicable to the detection of this reaction.
Immune serums were obtained from rats, which reacted specifically with rabbit acute-phase serums, but only weakly with normal rabbit serum. The Cx-reactive protein appearing in the blood of rabbits in the acute phase of inflammatory reactions to inoculation with various agents (pneumococcus andH.pertussis cultures, diphtheria toxin,E.coli culture filtrates, pyrogens) was immunologically identical, irrespective of the nature of the agent used.
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Khai, L.M. Experimental study of acute-phase reactions. Bull Exp Biol Med 46, 1202–1205 (1958). https://doi.org/10.1007/BF00788064
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DOI: https://doi.org/10.1007/BF00788064