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Cellulose phosphate—A new agent for stabilizing donor blood

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Pharmaceutical Chemistry Journal Aims and scope

Conclusions

  1. 1.

    Conditions for preparing a fibrous cation exchanger of optimum composition and possessing in its dynamics high sorptive properties which permit its use as a stabilizer of donated blood were developed, using as its basis the phosphorylation of cellulose in the form of medicinal gauze.

  2. 2.

    It was shown that it is possible to regulate the acidity of the stabilized blood and also the admittance of small amounts of inorganic phosphorus into it by fixing the degree to which the ionogenic groups are substituted with sodium.

  3. 3.

    The fibrous cation exchanger obtained, cellulose phosphate, is not pyrogenic nor toxic. Its satisfactory chemical, thermal, and radiation stability makes it possible to employ sterilization by autoclaving or radiation.

  4. 4.

    A method of preserving donor blood, which makes it possible to obtain blood close to normal, is proposed and is based on the use of the sorbent we have just studied.

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Authors and Affiliations

  1. Institute of General and Inorganic Chemistry, Academy of Sciences of the Belorussian SSR, USSR

    I. N. Ermolenko, E. D. Buglov, I. P. Lyubliner, S. I. Dovgalev, I. P. Danilov & M. L. Longin

  2. Belorussian Research Institute of Hematology and Blood Transfusion, Minsk

    I. N. Ermolenko, E. D. Buglov, I. P. Lyubliner, S. I. Dovgalev, I. P. Danilov & M. L. Longin

Authors
  1. I. N. Ermolenko
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  2. E. D. Buglov
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  3. I. P. Lyubliner
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  4. S. I. Dovgalev
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  5. I. P. Danilov
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  6. M. L. Longin
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 12, pp. 33–39, December, 1968.

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Ermolenko, I.N., Buglov, E.D., Lyubliner, I.P. et al. Cellulose phosphate—A new agent for stabilizing donor blood. Pharm Chem J 2, 681–686 (1968). https://doi.org/10.1007/BF00763333

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  • DOI: https://doi.org/10.1007/BF00763333

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