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Experimental production of leptomeningeal heterotopias from dissociated fetal tissue

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Summary

Subarachnoid heterotopias were produced experimentally in rats by intracisternal injection of dissociated fetal brain tissue. Heterotopias contained neurons and glial tissue and also mesodermal tissue including striated skeletal muscle. The data show that particles of disintegrated germinal tissue can survive, redistribute, settle and mature within the CSF spaces.

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Author notes

  1. K. Tamagawa

    Present address: Tokyo Metropolitan Neurological Hospital, Tokyo, Japan

Authors and Affiliations

  1. Abteilung für Neuropathologie, Universität Göttingen, Robert-Koch-Strasse 40, D-3400, Göttingen, Federal Republic of Germany

    K. Tamagawa & R. L. Friede

  2. Abteilung für Neurologie, Universität Göttingen, Robert-Koch-Strasse 40, D-3400, Göttingen, Federal Republic of Germany

    P. Scheidt

Authors
  1. K. Tamagawa
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  2. P. Scheidt
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  3. R. L. Friede
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Tamagawa, K., Scheidt, P. & Friede, R.L. Experimental production of leptomeningeal heterotopias from dissociated fetal tissue. Acta Neuropathol 78, 153–158 (1989). https://doi.org/10.1007/BF00688203

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  • DOI: https://doi.org/10.1007/BF00688203

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