Summary
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1.
The fatty acid composition and cholesterol/phospholipid molar ratio of lipids extracted from subcellular fractions of 5–6, 10, and 20 day chick embryo heart and from adult chicken heart were determined.
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2.
The fraction of saturated fatty acids decreases steadily during embryonic and post-hatching development.
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3.
The cholesterol/phospholipid molar ratio decreases between 5–6 and 10 days of embryonic life, increases somewhat between 10 and 20 days of incubation, and decreases again during post-hatching development.
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4.
The pattern of changes in lipid composition is similar in the plasma membrane enriched fraction, the fraction enriched in mitochondria and endoplasmic reticulum, and in the homogenate.
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5.
The changes in the fatty acid composition and cholesterol/phospholipid molar ratio that occur during development are consistent with developmental changes in the microviscosity of the plasma membrane enriched fraction that we previously reported.
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Kutchai, H., Ross, T.F., Dunning, D.M. et al. Developmental changes in the fatty acid composition and cholesterol content of chicken heart plasma membrane. J Comp Physiol B 125, 151–156 (1978). https://doi.org/10.1007/BF00686751
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DOI: https://doi.org/10.1007/BF00686751