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Distinct presentations of radiocontrast-induced sialadenitis in renal insufficients and in patients with normal renal function

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Abstract

We report two incide ntal observations of radiocontrast-induced sialadenitis which occurred in a patient with normal renal function and in another patient undergoing chronic haemodialysis. Our first observation consisted of parotid gland, enlargement noted 1 h after contrast injection and which presaged anaphy lactoid shock. In the second cast salivary gland enlargement developed 3 days after administration of iodinated agent. A review of the literature based on 27 published observations. In dicates that two different presentations of iodide-induced sialadenitis canbe recognisedaccording totheirpathogenesis. In patients with normally functioning kidneys, the occurrence of sialadenitis after a shortdelay(5 min to 24 h) evokes an anaphylactoidmechanism. Conversely, in patients with impaired renal function, the delayed onset (1–5 days) of this adverse reaction suggest a toxic effect.

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References

  1. Katayama H, Yamaguchi K, Kozuka T, Takashima T, Seez P, Matsuura K (1991) Adverse reaction to ionic and nonionic contrast media: a report from the Japanese Committe on the safety of contrast media. Radiology 175: 621–628

    Google Scholar 

  2. Palmer FJ (1988) The RACR survey of intravenous contrast media reactions: a preliminary report. Aust Radiol 23: 8–11

    Google Scholar 

  3. Pinet A, Lyonnet D, Maillet P, Groleau JM (1982) Adverse reactions to intravenous contrast media in urography: results of a national survey. In: Amiel M (ed) Contrast media in radiology. Springer, Berlin Heidelberg New York, pp 14–15

    Google Scholar 

  4. Panto PN, Davies P (1988) Delayed reactions to urographic contrast media. Br J Radiol 59: 41–44

    Google Scholar 

  5. Wylie EJ, Mitchell DB (1991) Case report: iodide mumps following intravenous urography with iopamidol. Clin Radiol 43: 135–136

    Google Scholar 

  6. McCullough M, Davies P, Richardson R (1989) A large trial of intravenous Conray 325 and Niopam 300 to assess immediate and delayed reactions. Br J Radiol 62: 260–265

    Google Scholar 

  7. Talner LB, Lang JH, Brasch RC, Lasser EC (1971) Elevated salivary iodine and salivary gland enlargement due to iodinated contrast media. AJR 112: 380–382

    Google Scholar 

  8. Park FR, Cronk RT, Cronk GE (1953) Prevention of iodism in bronchography by use of ACTH: case report. Dis Chest 232: 219–255

    Google Scholar 

  9. Lasser EC (1969) Sialadenopathy due to cholecystographic contrast media. JAMA 207: 2291–2292

    Google Scholar 

  10. Wolf M, Leventon G (1990) Acute iodide-induced enlargement of the salivary glands. J Oral Maxillofac Surg 48: 71–72

    Google Scholar 

  11. Koch RL, Byl FM, Firpo JJ (1969) Parotid swelling with facial paralysis: complication of intravenous urography. Radiology 92: 1043–1044

    Google Scholar 

  12. Harden RM (1968) Submandibular adenitis due to iodide administration. BMJ 1: 161–160

    Google Scholar 

  13. Imbur DJ (1972) Iodide mumps following excretory urography. J Urol 108: 629–630

    Google Scholar 

  14. Cohen JC, Roxe DM, Said R, Cummins G (1980) Iodide mumps after repeated exposure to iodinated contrast media. Lancet 1: 762–763

    Google Scholar 

  15. Harris PF, Sanchez JF, Mode DG (1970) Iodide mumps. JAMA 213: 2271–2272

    Google Scholar 

  16. Nakadar AS, Harris-Jones JN (1971) Sialadenitis after intravenous pyelography. BMJ 3: 351–352

    Google Scholar 

  17. Lang JH, Lasser EC, Talner LB, Lyon S, Coel M (1974) Inorganic iodide in contrast media. Invest Radiol 9: 51–55

    Google Scholar 

  18. Talner LB, Coel MC, Lang JH (1973) Salivary secretion of iodine after urography. Radiology 106: 263–268

    Google Scholar 

  19. Papadopoulos S, MacFarlane S, Harden RMcG (1966) Iodine excretion in urine, saliva, gastric juice and sweat in dehalogenase deficiency. J Endocrinol 36: 341–346

    Google Scholar 

  20. Davidson DC, Ford JA, Fox EG (1974) Iodide sialadenitis in childhood. Arch Dis Child 49: 67–68

    Google Scholar 

  21. Goldberg R, Grossman H, St Louis EL, Gray RR (1984) Contrast induced sialadenitis: a case report. J Otolaryngol 13: 331–332

    Google Scholar 

  22. Holder LE (1973) Acute parotid swelling following intravenous injections of iodinated contrast medium. Urology 2: 550–551

    Google Scholar 

  23. Ilia R, Gussarsky Y, Gueron M (1986) Salivary gland enlargement following cardiac catheterization. Cathet Cardiovasc Diagn 12: 163–164

    Google Scholar 

  24. Navani S, Taylor CE, Kaufman SA, Parlee RH (1972) Evanescent enlargement of salivary glands following tri-iodinated contrast media. Br J Radiol 45: 19–20

    Google Scholar 

  25. Sussman RM, Miller J (1956) Iodide “mumps” after intravenous urography. N Engl J Med 255: 433–434

    Google Scholar 

  26. Carter JE (1961) Iodide “mumps”. N Engl J Med 264: 987–988

    Google Scholar 

  27. Kohri K, Miyoshi S, Nagahara A, et al (1977) Bilateral parotid enlargement (“iodide mumps”) following excretory urography. Radiology 122: 654

    Google Scholar 

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Melki, P.S., Mugel, T., Cléro, B. et al. Distinct presentations of radiocontrast-induced sialadenitis in renal insufficients and in patients with normal renal function. Eur. Radiol. 4, 254–257 (1994). https://doi.org/10.1007/BF00606456

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  • DOI: https://doi.org/10.1007/BF00606456

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