Abstract
We report two incide ntal observations of radiocontrast-induced sialadenitis which occurred in a patient with normal renal function and in another patient undergoing chronic haemodialysis. Our first observation consisted of parotid gland, enlargement noted 1 h after contrast injection and which presaged anaphy lactoid shock. In the second cast salivary gland enlargement developed 3 days after administration of iodinated agent. A review of the literature based on 27 published observations. In dicates that two different presentations of iodide-induced sialadenitis canbe recognisedaccording totheirpathogenesis. In patients with normally functioning kidneys, the occurrence of sialadenitis after a shortdelay(5 min to 24 h) evokes an anaphylactoidmechanism. Conversely, in patients with impaired renal function, the delayed onset (1–5 days) of this adverse reaction suggest a toxic effect.
References
Katayama H, Yamaguchi K, Kozuka T, Takashima T, Seez P, Matsuura K (1991) Adverse reaction to ionic and nonionic contrast media: a report from the Japanese Committe on the safety of contrast media. Radiology 175: 621–628
Palmer FJ (1988) The RACR survey of intravenous contrast media reactions: a preliminary report. Aust Radiol 23: 8–11
Pinet A, Lyonnet D, Maillet P, Groleau JM (1982) Adverse reactions to intravenous contrast media in urography: results of a national survey. In: Amiel M (ed) Contrast media in radiology. Springer, Berlin Heidelberg New York, pp 14–15
Panto PN, Davies P (1988) Delayed reactions to urographic contrast media. Br J Radiol 59: 41–44
Wylie EJ, Mitchell DB (1991) Case report: iodide mumps following intravenous urography with iopamidol. Clin Radiol 43: 135–136
McCullough M, Davies P, Richardson R (1989) A large trial of intravenous Conray 325 and Niopam 300 to assess immediate and delayed reactions. Br J Radiol 62: 260–265
Talner LB, Lang JH, Brasch RC, Lasser EC (1971) Elevated salivary iodine and salivary gland enlargement due to iodinated contrast media. AJR 112: 380–382
Park FR, Cronk RT, Cronk GE (1953) Prevention of iodism in bronchography by use of ACTH: case report. Dis Chest 232: 219–255
Lasser EC (1969) Sialadenopathy due to cholecystographic contrast media. JAMA 207: 2291–2292
Wolf M, Leventon G (1990) Acute iodide-induced enlargement of the salivary glands. J Oral Maxillofac Surg 48: 71–72
Koch RL, Byl FM, Firpo JJ (1969) Parotid swelling with facial paralysis: complication of intravenous urography. Radiology 92: 1043–1044
Harden RM (1968) Submandibular adenitis due to iodide administration. BMJ 1: 161–160
Imbur DJ (1972) Iodide mumps following excretory urography. J Urol 108: 629–630
Cohen JC, Roxe DM, Said R, Cummins G (1980) Iodide mumps after repeated exposure to iodinated contrast media. Lancet 1: 762–763
Harris PF, Sanchez JF, Mode DG (1970) Iodide mumps. JAMA 213: 2271–2272
Nakadar AS, Harris-Jones JN (1971) Sialadenitis after intravenous pyelography. BMJ 3: 351–352
Lang JH, Lasser EC, Talner LB, Lyon S, Coel M (1974) Inorganic iodide in contrast media. Invest Radiol 9: 51–55
Talner LB, Coel MC, Lang JH (1973) Salivary secretion of iodine after urography. Radiology 106: 263–268
Papadopoulos S, MacFarlane S, Harden RMcG (1966) Iodine excretion in urine, saliva, gastric juice and sweat in dehalogenase deficiency. J Endocrinol 36: 341–346
Davidson DC, Ford JA, Fox EG (1974) Iodide sialadenitis in childhood. Arch Dis Child 49: 67–68
Goldberg R, Grossman H, St Louis EL, Gray RR (1984) Contrast induced sialadenitis: a case report. J Otolaryngol 13: 331–332
Holder LE (1973) Acute parotid swelling following intravenous injections of iodinated contrast medium. Urology 2: 550–551
Ilia R, Gussarsky Y, Gueron M (1986) Salivary gland enlargement following cardiac catheterization. Cathet Cardiovasc Diagn 12: 163–164
Navani S, Taylor CE, Kaufman SA, Parlee RH (1972) Evanescent enlargement of salivary glands following tri-iodinated contrast media. Br J Radiol 45: 19–20
Sussman RM, Miller J (1956) Iodide “mumps” after intravenous urography. N Engl J Med 255: 433–434
Carter JE (1961) Iodide “mumps”. N Engl J Med 264: 987–988
Kohri K, Miyoshi S, Nagahara A, et al (1977) Bilateral parotid enlargement (“iodide mumps”) following excretory urography. Radiology 122: 654
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Melki, P.S., Mugel, T., Cléro, B. et al. Distinct presentations of radiocontrast-induced sialadenitis in renal insufficients and in patients with normal renal function. Eur. Radiol. 4, 254–257 (1994). https://doi.org/10.1007/BF00606456
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DOI: https://doi.org/10.1007/BF00606456