Skip to main content
SpringerLink
Log in

Biological balance of sodium and potassium

A control system with oscillating correcting variable

  • Published:
Pflügers Archiv Aims and scope Submit manuscript

Summary

The rhythm of renal sodium and potassium excretion was measured in 4-h-intervals in 12 subjects. Each person exhibited clear circadian variations of each variable with a maximum between 8 a.m. and 4 p.m. In each subject and for both circadian rhythms the oscillation mean was correlated to the range of oscillation (amplitude).

Increase in sodium or potassium excretion during 1 day resulted in an increase of oscillation range. The oscillation means of sodium and potassium periodicity did not correlate.

The properties of biological control systems with oscillating correcting variables are comparable to those of technical control systems. The significance of circadian rhythm for the control of electrolyte balance is indicated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Aschoff, J.: Gesetzmäßigkeiten der biologischen Tagesperiodik. Dtsch. med. Wschr.88, 1930–1937 (1963)

    Google Scholar 

  2. Aschoff, J., Wever, R.: Biologische Rhythmen und Regelung. In: Probleme der zentralnervösen Regulation, Bad Oeynhausener Gespräche, 1962

  3. Aschoff, J., Klotter, K., Wever, R.: Circadian vocabulary. In: Circadian clocks (Aschoff, ed.), pp. X–XIX. Amsterdam 1965

  4. Bahlmann, I., McDonald, S. I., Veutom, M. G., De Wardener, H. E.: The effect on urinary sodium excretion of blood volume expansion without changing the composition of blood in the dog. Clin. Sci.32, 404–413 (1967)

    Google Scholar 

  5. Baldwin, D., Alexander, R. W., Warner, E. G.: Chronic sodium chloride challenge studies in man. J. Lab. clin. Med.55, 362–375 (1960)

    Google Scholar 

  6. Buchborn, E., Koczorek, K. R., Wolff, H. P.: Aldosteronausscheidung und tubuläre Nierenfunktion. Klin. Wschr.35, 452–459 (1957)

    Google Scholar 

  7. Campbell, I. A., Webster, T. A.: XIV. Note on urinary and excretory rhythms. Biochem. J.16, 507–513 (1922)

    Google Scholar 

  8. Gerritzen, F.: Der 24-Stunden-Rhythmus in der Diurese. Dtsch. med. Wschr.64, 746–748 (1938)

    Google Scholar 

  9. Goldman, R.: Studies in diurnal variation of water and electrolyte excretion: Nocturnal diuresis of water and sodium in congestive cardiac failure and cirrhosis of the liver. J. clin. Invest.30, 1191–1199 (1951)

    Google Scholar 

  10. Halberg, F., Engel, R., Swank, R., Seaman, G., Hissen, W.: Cosinor-Auswertung circadianer Rhythmen mit niedriger Amplitude im menschlichen Organismus. Physik. Med. und Rehab.7, 101–107 (1966)

    Google Scholar 

  11. Holzgreve, H., Schrier, R. W., Eigler, J.: Renale Regulation des natriumhaushaltes. Internist12, 69–76 (1971)

    Google Scholar 

  12. Hun Ki Min, Jones, I. E., Flink, E. B.: Circadian variations in renal excretion of magnesium, calcium, phosphorus, sodium, and potassium during frequent feeding and fasting. Fed. Proc.25, 917–921 (1966)

    Google Scholar 

  13. Klahr, S., Slatopolsky, E.: Renal regulation of sodium excretion. Arch. intern. Med.131, 780–791 (1973)

    Google Scholar 

  14. Mann, H., Rutenfranz, J., Wever, R.: Untersuchungen zur Tagesperiodik der Reaktionszeit bei Nachtarbeit. II. Beziehungen zwischen Gleichwert und Schwingungsbreite. Int. Arch. Arbeitsmed.29, 175–187 (1972)

    Google Scholar 

  15. Menzel, W.: Menschliche Tag- und Nachtrhythmik und Schichtarbeit. Basel: Schwabe Verlag 1962

    Google Scholar 

  16. Menzel, W., Blume, I., Silver, R., Luca, E.: Über die Periodik der Nierentätigkeit bei Gesunden und Nierenkranken. Verh. Arch. Ges. inn. Med.58, 292–294 (1952)

    Google Scholar 

  17. Oppelt, W.: Kleines Handbuch technischer Regelvorgänge. Weinheim: Verlag Chemie GmbH 1954

    Google Scholar 

  18. Reinhardt, H. W., Behrenbeck, D. W.: Untersuchungen an wachen Hunden über die Einstellung der Natriumbilanz. I. Die Bedeutung des Extracellulärraumes für die Einstellung der Natrium-Tagesbilanz. Pflügers Arch. ges. Physiol.295, 266–279 (1967)

    Google Scholar 

  19. Runcie, I.: Urinary sodium and potassium excretion in fasting obese subjects. Brit. med. J. 1971II, 22–25

    Google Scholar 

  20. Schultze, R. G.: Recent advances in the physiology and pathophysiology of potassium excretion. Arch. intern. Med.131, 885–897 (1973)

    Google Scholar 

  21. Strauss, M. B., Lamdin, E., Smith, W. P., Bleifer, D. J.: Surfeit and deficit of sodium. Arch. intern. Med.102, 527–536 (1958)

    Google Scholar 

  22. Wisser, H., Doerr, P., Stamm, D., Fatranska, R., Giedke, H., Wever, R.: Tagesperiodik der Ausscheidung von Elektrolyten, Katecholaminmetaboliten und 17-Hydroxycorticosteroiden im Harn. Klin. Wschr.51, 242–246 (1973)

    Google Scholar 

  23. Wever, R.: Zum Problem der Regelung in der Biologie. Pflügers Arch. ges. Physiol.278, 89–90 (1963a)

    Google Scholar 

  24. Wever, R.: Zum Mechanismus der biologischen 24-Stunden-Periodik. II. Mitteilung: Der Einfluß des Gleichwertes auf die Eigenschaften selbsterregter Schwingungen. Kybernetik,1, 213–231 (1963b)

    Google Scholar 

  25. Wever, R.: Ein mathematisches Modell für die circadiane Periodik. Z. angew. Math. Mech.46, 148–157 (1966)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Abteilung Innere Medizin II und Rechenzentrum der Rheinisch-Westfälischen Technischen Hochschule Aachen, Goethestrasse 27/29, D-5100, Aachen, Germany

    H. Mann, S. Stiller & R. Korz

Authors
  1. H. Mann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Stiller
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Korz
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mann, H., Stiller, S. & Korz, R. Biological balance of sodium and potassium. Pflugers Arch. 362, 135–139 (1976). https://doi.org/10.1007/BF00583639

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00583639

Key words

Search

Navigation