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Bubble column bioreactors

I. Methods for measuring the bubble size

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Summary

The photographic and electrical conductivity methods to measure the structure of two phase flow, especially bubble size, bubble frequency, local gas hold-up and, for the latter, the bubble velocity are described.

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Abbreviations

\(a = \frac{{a'}}{{V_L }}\) :

specific interfacial area

a′:

gas/liquid interfacial area

B:

constant in Eq. (4)

d:

diameter of the bubbles

d:

mean diameter of the bubbles

dS :

Sauter diameter

EG :

relative gas hold up

I:

current

kL :

mass transfer coefficient across the gas/liquid interface

kL′ :

local kL

\(k_L * = \frac{{k_L a}}{{a/2}}\) :

LT−1

\(k_L = \frac{{k_L a}}{a}\) :

LT−1

Δ1:

longitudinal distance between the start and stop sensors

Δ1B :

pierced length of the bubble

t:

time

Δt1 :

length of the square-wave signal at the start sensor

Δt2 :

length of the square-wave signal at the stop sensor

Δt12 :

time delay between start and stop signals

V:

volume of the bubbling layer

VL :

volume of the bubble free layer

VB :

bubble volume

vB :

bubble velocity

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Buchholz, R., Schügerl, K. Bubble column bioreactors. European J. Appl. Microbiol. Biotechnol. 6, 301–313 (1979). https://doi.org/10.1007/BF00499160

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  • DOI: https://doi.org/10.1007/BF00499160

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