Abstract
Evidence for the identity of β-galactosidase and β-fucosidase enzymes in the house mouse was obtained by examination of the enzyme activities in animals from different crosses between C57BL/Kl mice with high galactosidase and fucosidase activities and DBA/2/Kl mice with low activities. There is a strong correlation between the activities of these two enzymes in different tissues of F2 animals. A comparison of the fractionation properties of β-galactosidase and β-fucosidase showed that the two activities had a parallel distribution and identical thermostability. These data suggest that the same enzyme catalyzes the hydrolysis of both substrates.
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This work was supported by the Nilsson-Ehle fund and the Marcus Borgström fund.
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Seyedyazdani, R., Lundin, LG. Genetic relationship between β-galactosidase and β-fucosidase in the mouse. Biochem Genet 12, 441–448 (1974). https://doi.org/10.1007/BF00486061
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DOI: https://doi.org/10.1007/BF00486061