Skip to main content
Log in

An investigation of the products of 53 gene loci in three species of wild Canidae: Canis lupus, Canis latrans, and Canis familiaris

  • Published:
Biochemical Genetics Aims and scope Submit manuscript

Abstract

This article describes an investigation of inter- and intraspecific variation in three small populations of wild Canidae—wolf, coyote, and dingo. The products of 53 gene loci were examined. Very little interspecies variation was observed, but the level of intraspecific variation was compatible with that found in man.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Baur, E. W., and Schorr, R. T. (1969). Genetic polymorphism of tetrazolium oxidase in dogs. Science 1661524.

    Google Scholar 

  • Beckman, G., Lundgren, E., and Tarnvik, A. (1973). Superoxide dismutase isozymes in different human tissues, their genetic control and intracellular localisation. Hum. Hered. 23338.

    Google Scholar 

  • Boyd, J. W. (1961). The intracellular distribution, latency and electrophoretic mobility of L-glutamate-oxaloacetate transaminase from rat liver. Biochem. J. 81434.

    Google Scholar 

  • Braend, M., and Anstad, R. (1973). Polymorphism of red cell acid phosphatase in dogs. Anim. Blood Grps. Biochem. Genet. 4189.

    Google Scholar 

  • Bull, R. W., Bowdler, A. J., Templeton, J. W., Erickson, L. F., and Mayberry, M. B. (1972). Red cell antigens of wild Canidae. Anim. Blood Grps. Biochem. Genet. 3179.

    Google Scholar 

  • Christie, G. S., and Judah, J. D. (1953). Intracellular distribution of enzymes. Proc. R. Soc. London Ser. B 141420.

    Google Scholar 

  • Coates, P. M., Mestriner, M. A., and Hopkinson, D. A. (1975). A preliminary genetic interpretation of the esterase isozymes of human tissues. Ann. Hum. Genet. 391.

    Google Scholar 

  • Cohen, P. T. W., and Omenn, G. S. (1972). Genetic variation of the cytoplasmic and mitochondrial malic enzymes in the monkey Macaca nemestrina. Biochem. Genet. 7289.

    Google Scholar 

  • Edwards, Y. E., Clark, P., and Harris, H. (1976). Isozymes of glyceraldehyde-3-phosphate dehydrogenase in man and other mammals. Ann. Hum. Genet. 40:in press.

  • Fisher, R. A., and Harris, H. (1972). ‘Secondary’ isozymes derived from the three PGM loci. Ann. Hum. Genet. 3669.

    Google Scholar 

  • Harris, H., and Hopkinson, D. A. (1976). Handbook of Enzyme Electrophoresis, North-Holland, Amsterdam.

    Google Scholar 

  • Harris, H., Hopkinson, D. A., and Robson, E. B. (1974). The incidence of rare alleles determining electrophoretic variants: Data on 43 enzyme loci in man. Ann. Hum. Genet. 37237.

    Google Scholar 

  • Hopkinson, D. A. (1976). Personal communication.

  • Hopkinson, D. A., and Harris, H. (1969). The investigation of reactive sulphydryls in enzymes and their variants by starch gel electrophoresis: Studies on red cell adenosine deaminase. Ann. Hum. Genet. 3381.

    Google Scholar 

  • Hopkinson, D. A., Peters, J., and Harris, H. (1974). Rare electrophoretic variants of glycerol-3-phosphate dehydrogenase: Evidence for two structural gene loci (GPD 1and GPD 2). Ann. Hum. Genet. 37477.

    Google Scholar 

  • Khoo, J. C., and Russell, P. J. (1972). Isozymes of adenylate kinase in human tissue. Biochim. Biophys. Acta 26898.

    Google Scholar 

  • King, M.-C., and Wilson, A. C. (1975). Evolution at two levels in humans and chimpanzees. Science 188107.

    Google Scholar 

  • Koen, A. L., and Goodman, M. (1969). Aconitate hydratase isozymes: Subcellular location, tissue distribution and possible subunit structure. Biochim. Biophys. Acta 191698.

    Google Scholar 

  • Meera Khan, P., Los, W. R. T., Does, J. A., and Epstein, R. B. (1973). Isoenzyme markers in dog blood cells. Transplantation 15624.

    Google Scholar 

  • Quick, C. B., Fisher, R. A., and Harris, H. (1972). Differentiation of the PGM 2 locus isozymes from those of PGM 1and PGM 3 in terms of phosphopentomutase activity. Ann. Hum. Genet. 35445.

    Google Scholar 

  • Rapley, S., Lewis, W. H. P., and Harris, H. (1971). Tissue distribution substrate specificities and molecular sizes of human peptidases determined by separate gene loci. Ann. Hum. Genet. 34307.

    Google Scholar 

  • Rogers, P. A., Fisher, R. A., and Harris, H. (1975). An electrophoretic study of the distribution and properties of human hexokinases. Biochem. Genet. 13857.

    Google Scholar 

  • Saison, R. (1973). Red cell peptidase polymorphism in pigs, cattle, dogs and mink. Vox Sang. 25173.

    Google Scholar 

  • Simonsen, V. (1976). Electrophoretic studies on the blood proteins of domestic dogs and other Canidae. Hereditas 827.

    Google Scholar 

  • Smith, M., Hopkinson, D. A., and Harris, H. (1971). Developmental changes and polymorphism in human alcohol dehydrogenase. Ann. Hum. Genet. 34251.

    Google Scholar 

  • Smith, M., Hopkinson, D. A., and Harris, H. (1972). Alcohol dehydrogenase isozymes in adult human stomach and liver: Evidence for activity of the ADH 3locus. Ann. Hum. Genet. 35243.

    Google Scholar 

  • Swallow, D. M., and Harris, H. (1972). A new variant of placental acid phosphatases: Its implications regarding their subunit structures and genetical determination. Ann. Hum. Genet. 36141.

    Google Scholar 

  • Swallow, D. M., Povey, S., and Harris, H. (1973). Activity of the “red cell” acid phosphatase locus in other tissues. Ann. Hum. Genet. 3731.

    Google Scholar 

  • Turner, B. M., Fisher, R. A., and Harris, H. (1974). A comparison of the soluble and mitochondrial forms of human isocitrate dehydrogenase and an examination of the secondary isozymes derived from the soluble form. Ann. Hum. Genet. 37455.

    Google Scholar 

  • Weiden, P., Storb, R., Kolb, H. J., Graham, T., Anderson, J., and Giblett, E. (1974). Genetic variation of red blood cell enzymes in the dog. Transplantation 17115.

    Google Scholar 

  • Wilson, D. E., Jr., Povey, S., and Harris, H. (1976). Adenylate kinases in man: Evidence for a third locus. Ann. Hum. Genet. 39305.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fisher, R.A., Putt, W. & Hackel, E. An investigation of the products of 53 gene loci in three species of wild Canidae: Canis lupus, Canis latrans, and Canis familiaris . Biochem Genet 14, 963–974 (1976). https://doi.org/10.1007/BF00485128

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00485128

Key words

Navigation