Abstract
This article describes an investigation of inter- and intraspecific variation in three small populations of wild Canidae—wolf, coyote, and dingo. The products of 53 gene loci were examined. Very little interspecies variation was observed, but the level of intraspecific variation was compatible with that found in man.
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Baur, E. W., and Schorr, R. T. (1969). Genetic polymorphism of tetrazolium oxidase in dogs. Science 1661524.
Beckman, G., Lundgren, E., and Tarnvik, A. (1973). Superoxide dismutase isozymes in different human tissues, their genetic control and intracellular localisation. Hum. Hered. 23338.
Boyd, J. W. (1961). The intracellular distribution, latency and electrophoretic mobility of L-glutamate-oxaloacetate transaminase from rat liver. Biochem. J. 81434.
Braend, M., and Anstad, R. (1973). Polymorphism of red cell acid phosphatase in dogs. Anim. Blood Grps. Biochem. Genet. 4189.
Bull, R. W., Bowdler, A. J., Templeton, J. W., Erickson, L. F., and Mayberry, M. B. (1972). Red cell antigens of wild Canidae. Anim. Blood Grps. Biochem. Genet. 3179.
Christie, G. S., and Judah, J. D. (1953). Intracellular distribution of enzymes. Proc. R. Soc. London Ser. B 141420.
Coates, P. M., Mestriner, M. A., and Hopkinson, D. A. (1975). A preliminary genetic interpretation of the esterase isozymes of human tissues. Ann. Hum. Genet. 391.
Cohen, P. T. W., and Omenn, G. S. (1972). Genetic variation of the cytoplasmic and mitochondrial malic enzymes in the monkey Macaca nemestrina. Biochem. Genet. 7289.
Edwards, Y. E., Clark, P., and Harris, H. (1976). Isozymes of glyceraldehyde-3-phosphate dehydrogenase in man and other mammals. Ann. Hum. Genet. 40:in press.
Fisher, R. A., and Harris, H. (1972). ‘Secondary’ isozymes derived from the three PGM loci. Ann. Hum. Genet. 3669.
Harris, H., and Hopkinson, D. A. (1976). Handbook of Enzyme Electrophoresis, North-Holland, Amsterdam.
Harris, H., Hopkinson, D. A., and Robson, E. B. (1974). The incidence of rare alleles determining electrophoretic variants: Data on 43 enzyme loci in man. Ann. Hum. Genet. 37237.
Hopkinson, D. A. (1976). Personal communication.
Hopkinson, D. A., and Harris, H. (1969). The investigation of reactive sulphydryls in enzymes and their variants by starch gel electrophoresis: Studies on red cell adenosine deaminase. Ann. Hum. Genet. 3381.
Hopkinson, D. A., Peters, J., and Harris, H. (1974). Rare electrophoretic variants of glycerol-3-phosphate dehydrogenase: Evidence for two structural gene loci (GPD 1and GPD 2). Ann. Hum. Genet. 37477.
Khoo, J. C., and Russell, P. J. (1972). Isozymes of adenylate kinase in human tissue. Biochim. Biophys. Acta 26898.
King, M.-C., and Wilson, A. C. (1975). Evolution at two levels in humans and chimpanzees. Science 188107.
Koen, A. L., and Goodman, M. (1969). Aconitate hydratase isozymes: Subcellular location, tissue distribution and possible subunit structure. Biochim. Biophys. Acta 191698.
Meera Khan, P., Los, W. R. T., Does, J. A., and Epstein, R. B. (1973). Isoenzyme markers in dog blood cells. Transplantation 15624.
Quick, C. B., Fisher, R. A., and Harris, H. (1972). Differentiation of the PGM 2 locus isozymes from those of PGM 1and PGM 3 in terms of phosphopentomutase activity. Ann. Hum. Genet. 35445.
Rapley, S., Lewis, W. H. P., and Harris, H. (1971). Tissue distribution substrate specificities and molecular sizes of human peptidases determined by separate gene loci. Ann. Hum. Genet. 34307.
Rogers, P. A., Fisher, R. A., and Harris, H. (1975). An electrophoretic study of the distribution and properties of human hexokinases. Biochem. Genet. 13857.
Saison, R. (1973). Red cell peptidase polymorphism in pigs, cattle, dogs and mink. Vox Sang. 25173.
Simonsen, V. (1976). Electrophoretic studies on the blood proteins of domestic dogs and other Canidae. Hereditas 827.
Smith, M., Hopkinson, D. A., and Harris, H. (1971). Developmental changes and polymorphism in human alcohol dehydrogenase. Ann. Hum. Genet. 34251.
Smith, M., Hopkinson, D. A., and Harris, H. (1972). Alcohol dehydrogenase isozymes in adult human stomach and liver: Evidence for activity of the ADH 3locus. Ann. Hum. Genet. 35243.
Swallow, D. M., and Harris, H. (1972). A new variant of placental acid phosphatases: Its implications regarding their subunit structures and genetical determination. Ann. Hum. Genet. 36141.
Swallow, D. M., Povey, S., and Harris, H. (1973). Activity of the “red cell” acid phosphatase locus in other tissues. Ann. Hum. Genet. 3731.
Turner, B. M., Fisher, R. A., and Harris, H. (1974). A comparison of the soluble and mitochondrial forms of human isocitrate dehydrogenase and an examination of the secondary isozymes derived from the soluble form. Ann. Hum. Genet. 37455.
Weiden, P., Storb, R., Kolb, H. J., Graham, T., Anderson, J., and Giblett, E. (1974). Genetic variation of red blood cell enzymes in the dog. Transplantation 17115.
Wilson, D. E., Jr., Povey, S., and Harris, H. (1976). Adenylate kinases in man: Evidence for a third locus. Ann. Hum. Genet. 39305.
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Fisher, R.A., Putt, W. & Hackel, E. An investigation of the products of 53 gene loci in three species of wild Canidae: Canis lupus, Canis latrans, and Canis familiaris . Biochem Genet 14, 963–974 (1976). https://doi.org/10.1007/BF00485128
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DOI: https://doi.org/10.1007/BF00485128