Abstract
A further esterase, esterase 11, which exhibits a polymorphism detectable by electrophoresis, has been observed in the house mouse, Mus musculus. In 15 inbred strains and two outbred strains, the ES-11A phenotype has been found, composed of two bands of enzyme activity of greater anodal electrophoretic mobility than the two bands of the ES-11B phenotype found in one inbred strain, one wild stock, and 101 wild mice. In F1 hybrids (IS/Cam×C57 BL/Gr), the phenotype shown corresponds to a mixture of the two parental phenotypes. In backcrosses, ES-11 segregates as an autosomal gene, designated Es-11, closely linked to Es-2 and Es-5 on chromosome 8.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Berry, R. J., and Peters, J. (1977). Heterogeneous heterozygosities in Mus musculus populations. Proc. Roy. Soc. B (in press).
Chapman, V. M. (1975). 6-Phosphogluconate dehydrogenase (PGD) genetics in the mouse: Linkage with metabolically related enzyme loci. Biochem. Genet. 13849.
Chapman, V. M., Nichols, E. A., and Ruddle, F. H. (1974). Esterase-8 (Es-8): Characterization, polymorphism, and linkage of an erythrocyte esterase locus on chromosome 7 of Mus musculus. Biochem. Genet. 11347.
Coates, P. M., and Simpson, N. E. (1972). Genetic variation in human erythrocyte acetylcholinesterase. Science 1751466.
Coates, P. M., Mestriner, M. A., and Hopkinson, D. A. (1975). A preliminary genetic interpretation of the esterase isozymes of human tissues. Ann. Hum. Genet. 391.
DeLorenzo, R. J., and Ruddle, F. H. (1970). Glutamate oxalate transaminase (GOT) genetics in Mus musculus: Linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci. Biochem. Genet. 4259.
Oki, Y., and Miura, K. (1966). Genetic and physiological control of esterases in experimental small animals. II. Inheritance of liver esterase in mice. Tohoku J. Agr. Res. 1757.
Pantelouris, E.M., and Arnason, A. (1966). Ontogenesis of serum esterases in Mus musculus. J. Embryol. Exp. Morphol. 1655.
Peters, J., and Nash, H. R. (1976). Polymorphism of esterase 10 in Mus musculus. Biochem. Genet. 14119.
Petras, M. L. (1963). Genetic control of a serum esterase component in Mus musculus. Proc. Natl. Acad. Sci. 50112.
Petras, M. L., and Biddle, F. G. (1967). Serum esterases in the house mouse, Mus musculus. Can. J. Genet. Cytol. 9704.
Petras, M. L., and Sinclair, P. (1969). Another esterase variant in the kidney of the house mouse, Mus musculus. Can. J. Genet. Cytol. 1197.
Popp, R. A. (1966). Inheritance of an erythrocyte and kidney esterase in the mouse. J. Hered. 57197.
Popp, R. A., and Popp, D. M. (1962). Inheritance of serum esterases having different electrophoretic patterns among inbred strains of mice. J. Hered. 53111.
Roderick, T. H., Hutton, J. J., and Ruddle, F. H. (1970). Linkage of Esterase-3 and Rex on linkage group VII of the mouse. J. Hered. 61278.
Ruddle, F. H., and Roderick, T. H. (1966). The genetic control of two types of esterases in inbred strains of the mouse. Genetics 54191.
Ruddle, F. H., and Roderick, T. H. (1968). Allelically determined isozyme polymorphisms in laboratory populations of mice. Ann. N.Y. Acad. Sci. 151531.
Ruddle, F. H., Shows, T. B., and Roderick, T. H. (1968). Autosomal control of an electrophoretic variant of glucose-6-phosphate dehydrogenase in the mouse (Mus musculus). Genetics 58599.
Ruddle, F. H., Shows, T. B., and Roderick, T. H. (1969). Esterase genetics in Mus musculus: Expression, linkage and polymorphism of locus Es-2. Genetics 62393.
Schollen, J., Bender, K., and Von Deimling, O. (1975). Esterase. XXI. Es-9, a possibly new polymorphic esterase in Mus musculus genetically linked to Es-2. Biochem. Genet. 13369.
Selander, R. K., Yang, S. Y., and Hunt, W. G. (1969). Polymorphism in esterases and hemoglobin in wild populations of the house mouse (Mus musculus). Stud. Genet. V: Univ. Texas Publ. 6918271.
Templeton, M. (1969). Mouse erythrocyte esterases and an interaction with heparin as shown by starch gel electrophoresis. J. Histochem. Cytochem. 1795.
Wheeler, L. L., and Selander, R. K. (1972). Genetic variation in populations of the house mouse, Mus musculus, in the Hawaiian islands. Stud. Genet. VII: Univ. Texas Publ. 7213269.
Womack, J. E. (1975). Esterase-6 (Es-6) in laboratory mice: Hormone-influenced expression and linkage relationship to oligosyndactylism (Os), esterase-1 (Es-1), and esterase-2 (Es-2) in chromosome 8. Biochem. Genet. 13311.
Womack, J. E., and Sharp, M. (1976). Comparative autosomal linkage in mammals: Genetics of esterase in Mus musculus and Rattus norvegicus. Genetics 82665.
Author information
Authors and Affiliations
Additional information
This work was supported by the Medical Research Council.
Rights and permissions
About this article
Cite this article
Peters, J., Nash, H.R. Polymorphism of esterase 11 in Mus musculus, a further esterase locus on chromosome 8. Biochem Genet 15, 217–226 (1977). https://doi.org/10.1007/BF00484454
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00484454