Skip to main content
Log in

Measurement of nasal mucociliary activity in man with 99mTc-labelled resin particles

  • Published:
Archives of oto-rhino-laryngology Aims and scope Submit manuscript

Summary

The mucociliary activity in normal and pathological nasal mucosa was studied with a gamma camera using 99mTc-labelled resin particles. The mucus flow rate was investigated under physiological conditions in the following groups of subjects: normal, allergic rhinitis, vasomotor rhinitis, primary atrophic rhinitis, and laryngectomized. The mean flow rates obtained were 5.7±2.2, 1.5±0.5, 1.9±0.8, 0.0, and 4.8±1.9 mm/min respectively. When the results were compared, the differences between the normal and allergic rhinitis groups, and the normal and vasomotor rhinitis groups were statistically significant (p < 0.05). However, the differences between the normal and laryngectomized groups, and the allergic and vasomotor rhinitis groups were insignificant (p >0.05).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

references

  1. Andersen LB, Camner P, Jensen PL, Philipson K, Proctor DF (1974) A comparison of nasal and tracheobronchial clearance. Arch Environ Health 29: 290–293

    Google Scholar 

  2. Dolowitz DA, Dougherty TF (1971) Allergy as inflammatory reactions. Trans Am Acad Ophtalmol Otolaryngol 75: 829–836

    Google Scholar 

  3. Ewert G (1975) On the mucus flow rate in the human nose. Acta Otolaryngol (suppl) 200: 1–62

    Google Scholar 

  4. Guillerm R, Morcellet JL, Riu R, Renon P, Badre R, Hee J (1971) Etude du drainage muco-ciliaire nasal chez l'homme par scintigraphies séquentielles d'une particule marquée au technetium 99m. Ann Otolaryngol (paris) 88: 303–310

    Google Scholar 

  5. Kärjä J, Nuutinen J, Karjalainen P (1982) Radioisotopic method for measurement of nasal mucociliary activity. Arch Otolaryngol 108: 99–101

    Google Scholar 

  6. McAffee JG, Fueger CF, Stern HS, Wagner HN jr, Migita T (1964) 99mTc pertechnetate for brain scanning. J Nucl Med 5: 811–827

    Google Scholar 

  7. Prazic M, Weber K (1964) The quantitative values of mucin in respiratory tract in normal and pathological conditions. Acta Otolaryngol 57: 377–382

    Google Scholar 

  8. Proctor DF (1969) Measurement of mucociliary activity in man. Ann Otol Rhinol Laryngol 78: 518–531

    Google Scholar 

  9. Proctor DF, Wagner HN Jr (1965) Clearance of particles from the human nose (Preliminary report). Arch Environ Health 11: 366–371

    Google Scholar 

  10. Puchelle E, Aug F, Pham QT, Bertrand A (1981) Comparison of three methods for measuring nasal mucociliary clearance in man. Acta Otolaryngol 91: 297–303

    Google Scholar 

  11. Quinlan MF, Salman SD, Swift DL, Wagner HN Jr, Proctor DF (1969) Measurement of mucociliary function in man. Am Rev Respir Dis 99: 13–23

    Google Scholar 

  12. Rylander R (1966) Current techniques to measure alterations in the ciliary activity of intact respiratory epithelium. Am Rev Respir Dis 93: 67–72

    Google Scholar 

  13. Simon H, Drettner B, Jung B (1977) Messung des Schleimhauttransportes in menschlichen Nasen mit 51Cr markierten Harzkügelchen. Acta Otolaryngol 83: 378–389

    Google Scholar 

  14. Stahl RH (1974) Allergic disorders of the nose and paranasal sinuses. Otolaryngol Clin North Am 7: 703–718

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kaya, S., Ercan, M.T. & Laleli, Y. Measurement of nasal mucociliary activity in man with 99mTc-labelled resin particles. Arch Otorhinolaryngol 239, 267–272 (1984). https://doi.org/10.1007/BF00464254

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00464254

Key words

Navigation