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Congenital chloride diarrhoea in Kuwaiti children

  • Metabolic Diseases
  • Published:
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Abstract

Congenital chloride diarrhoea was diagnosed in 16 Kuwaiti children over a 7 year period (1980–1986) with an estimated incidence of 7.6 per 100,000 live births. The mean age at diagnosis was 3.2 months (range 1 week to 5 months). There were 9 boys and 7 girls with a mean age of 3 years 10 months (range 10 months to 7 years). All children had a shortened gestational period, abdominal distension and chronic diarrhoea. The serum electrolytes in all patients prior to treatment showed hyponatraemia, hypokalaemia, hypochloraemia and metabolic alkalosis. The diagnosis was confirmed by a stool chloride content that exceeded the sum of faecal sodium and potassium. Fifteen patients survived and showed catch-up growth with adequate replacement therapy and 1 died with renal failure.

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Abbreviations

CCD:

congenital chloride diarrhoea

FCL:

Faecal choride

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Authors and Affiliations

  1. Department of Paediatrics, Farwania Hospital, Farwania, P.O. Box 18373, 81004, Farwania, Kuwait

    M. M. Lubani, D. C. Sharda & T. S. Al-Shab

  2. Adan Hospital, Kuwait

    K. I. Doudin

  3. Mubarak Hospital, Kuwait

    Y. K. Abdul Al

  4. Amiri Hospital, Kuwait

    A. A. Shaltout

  5. Sabah Hospital, Kuwait

    M. A. Said

Authors
  1. M. M. Lubani
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  2. K. I. Doudin
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  3. D. C. Sharda
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  4. A. A. Shaltout
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  5. T. S. Al-Shab
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  6. Y. K. Abdul Al
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  7. M. A. Said
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Lubani, M.M., Doudin, K.I., Sharda, D.C. et al. Congenital chloride diarrhoea in Kuwaiti children. Eur J Pediatr 148, 333–336 (1989). https://doi.org/10.1007/BF00444128

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  • DOI: https://doi.org/10.1007/BF00444128

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