Abstract
In 1963, Klein et al. first described two girls with normokalemic periodic paralysis and cardiac arrhythmia. We have observed a 15-year-old girl with cardiac arrhythmia and normokalemia but with some features of hyperkalemic, periodic paralysis. The patient showed a waddling gait and Gower's sign. She had atrophy of the proximal muscles and deep tendon reflexes were reduced. Her ECG showed bigeminy with multifocal premature ventricular contractions. At the start of an episode of muscle weakness, the serum potassium concentration rose from 3.1 to 4.4 mEq/l. Muscle weakness was not provoked by intravenous administration of 45 g glucose or of 72 g glucose followed by 10 units of regular insulin. Muscle weakness was evoked by the ingestion of 4 g potassium chloride. During the provoked muscle weakness, the ECG showed normal sinus rhythm temporarily.
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References
Brooke MH (1977) A clinician's view of neuro-muscular disease. Baltimore, Williams and Wilkins Co, pp 182–194
Chesson AJ Jr, Schochet SS Jr, Peters BH (1979) Biphasic periodic paralysis. Arch Neurol 36:700–704
Klein R, Ganelin R, Marks JF, Usher P, Richards C (1963) Periodic paralysis with cardiac arrhythmia. J Pediatr 62:371–385
Levitt LP, Rose LI, Dawson DM (1972) Hypokalemic periodic paralysis with arrhythmia. N Engl J Med 286:253–254
Lisak RP, Lebeau J, Tucker SH, Rowland LP (1972) Hyperkalemic periodic paralysis and cardiac arrhythmia. Neurology 22: 810–815
Pearson CM (1964) The periodic paralyses: Differential features and pathologic observations in permanent myopathic weakness. Brain 87:341–353
Stubbs WA (1976) Bidirectional ventricular tachycardia in familiar hypokalemic periodic paralysis. Proc R Soc Med 69: 223–224
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Yoshimura, T., Kaneuji, M., Okuno, T. et al. Periodic paralysis with cardiac arrhythmia. Eur J Pediatr 140, 338–343 (1983). https://doi.org/10.1007/BF00442678
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DOI: https://doi.org/10.1007/BF00442678