Abstract
We have evaluated 46 patients with Turner syndrome by clinical examination, M-mode and two-dimensional echocardiography, dynamic exercise testing and 24h Holter monitoring. Twelve patients (26.1%) had mitral valve prolapse and 7 patients (15.2%) had isolated non stenotic bicuspid aortic valve. Aortic root dilation was present in 2 patients (4.3%). Our data indicate that incidence of mitral valve prolapse is significantly higher in Turner syndrome than in the general population (P<0.025).
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Allen DB, Hendricks SA, Levy JM (1986) Aortic dilation in Turner syndrome. J Pediatr 109:302–305
DeMaria AN, Bommer W, Joyce J, Lee G, Bouteller J, Mason DT (1980) Value and limitations of cross-sectional echocardiography of the aortic valve in the diagnosis and quantification of valvular aortic stenosis. Circulation 6:304–312
Haddad HM, Wilkins L (1959) Congenital anomalies associated with gonadal aplasia. Pediatrics 23:885–902
Hagerman RJ, Synhorst DP (1984) Mitral valve prolapse and aortic dilatation in the fragile X syndrome. Am J Med Genet 17:123–131
Jeresaty RM, Basu SK, Franco J (1972) Dissecting aneurysm of the aorty in Turner's syndrome. JAMA 222:574–576
Lemli L, Smith DW (1963) The X0 syndrome: a study of the differentiated phenotype in 25 patients. J Pediatr 63:577–588
Miller MJ, Geffner ME, Lippe BM, Itami RM, Kaplan SA, Di Sessa TG, Isabel-Jones JB, Friedman WF (1983) Echocardiography reveals a high incidence of bicuspid aortic valve in Turner syndrome. J Pediatr 102:47–50
Popp RL, Brown OR, Silverman JF, Harrison DC (1974) Echocardiographic abnormalities in the mitral valve prolapse syndrome. Circulation 49:428–433
Price WH, Wilson J (1983) Dissection of the aorta in Turner's syndrome. J Med Genet 20:61–63
Procacci PM, Savran MS, Schreiter MS, Bryson AL (1976) Prevalence of clinical mitral-valve prolapse in 1169 young women. N Engl J Med 294:1086–1088
Ranier-Pope CR, Cunningham RD, Nadas AS, Crigler JF (1964) Cardiovascular malformations in Turner's syndrome. Pediatrics 33:919–925
Russo L, Aloisi B, Ierna A, Centaro A, Negro R, Brancati B (1980) Scoliosis and mitral valve prolapse. An epidemiological and ethiopathogenetic screening. G Ital Cardiol 10:1001–1005
Slater DN, Grundman MJ Mitchell L (1982) Turner's syndrome associated with bicuspid aortic steoosis and dissecting aortic aneurysm. Postgrad Med J 58:436–438
Udoshi MB, Shah A, Fisher VJ, Dolgin M (1979) Incidence of mitral valve prolapse in subjects with thoracic skeletal abnormalities — a prospective study. Am Heart J 97:303–311
Wooley CF (1983) The mitral valve prolapse syndrome. Hosp Pract 18:163–169
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bastianon, V., Pasquino, A.M., Giglioni, E. et al. Mitral valve prolapse in Turner syndrome. Eur J Pediatr 148, 533–534 (1989). https://doi.org/10.1007/BF00441551
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00441551