Summary
The phenomenon of intergenic conversion (information transfer between dispersed but sequence-related genetic elements embedded in non homologous environments) has been demonstrated clearly in S. pombe as well as in other organisms. By analysing four particular aspects of intergenic conversion in S. pombe we reach the following conclusions: (1) The events are not RNA-mediated since transcription-deficient members of the serine tRNA gene family studied are as productive in intergenic information transfer as transcription-proficient members, (2) Intergenic recombination is not a reciprocal but a non-reciprocal process, (3) Intergenic conversion occurring at a particular locus does not influence crossing-over in the intervals adjacent to that locus, and (4) During meiosis the process occurs at the replicated (chromatid) stage rather than at the unreplicated (chromosome) stage.
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Junker, A., Lehmann, E. & Munz, P. Genetic analysis of particular aspects of intergenic conversion in Schizosaccharomyces pombe . Curr Genet 12, 119–125 (1987). https://doi.org/10.1007/BF00434666
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DOI: https://doi.org/10.1007/BF00434666