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Effects of propoxyphene, ethoheptazine, and azabicyclane on schedule-controlled responding: Attenuation by pentobarbital but not naloxone

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Abstract

The effects of propoxyphene, ethoheptazine, and azabicyclane, alone and in combination with 1 mg/kg naloxone, were studied in pigeons responding under a multiple fixed ratio, fixed interval schedule of food presentation. Low doses of pentobarbital (3, 5.6, and 10 mg/kg) attenuated the rate-decreasing effects produced by 20 mg/kg propoxyphene, ethoheptazine, and azabicyclane. Naloxone antagonized the rate-decreasing effects produced by 10 mg/kg azabicyclane but did not antagonize the rate-decreasing effects of propoxyphene or ethoheptazine.

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Leander, J.D. Effects of propoxyphene, ethoheptazine, and azabicyclane on schedule-controlled responding: Attenuation by pentobarbital but not naloxone. Psychopharmacology 66, 19–22 (1979). https://doi.org/10.1007/BF00431983

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  • DOI: https://doi.org/10.1007/BF00431983

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