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Effects of training on plasma FFA during exercise in women

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Summary

The purpose of this study was to investigate the effects of training on plasma FFA concentrations in women during 60 min of work. All subjects (n=10) exercised at 55% of their initial VO2 max for 60 min on a bicycle ergometer. Five subjects then participated in a training program, consisting of bicycling five days per week for four weeks while five control subjects remained inactive. Following the training or control period, all 10 subjects repeated the initial 1-h test at the same absolute work load. The training program resulted in a 14% increase in VO2 max and a decreased resting HR (p<0.05). The submaximal exercise HR and R were also lower following training (p<0.05). Plasma FFA were significantly lower (p<0.05) during exercise in the experimental group following training. The average increase in plasma FFA during the 60 min bicycle test was 0.22 Μmol/l, from 0.48 Μmol/l at rest to 0.70 Μmol/l after 60 min of exercise prior to training. After training the same absolute work load resulted in an increased plasma FFA of only 0.10 Μmol/l from 0.29 to 0.39 Μmol/l. No significant changes due to training were observed for glycerol or lactate. The results suggest that the metabolic response of women is similar to men during exercise before and after training. Possible mechanisms for the decreased plasma FFA response after training are discussed.

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References

  • Armstrong, D. T., Steele, R., Altszuler, N., Dunn, A., Bishop, J. S., DeBodo, C.: Regulation of plasma free fatty acid turnover. Am. J. Physiol. 201, 9–15 (1961)

    Google Scholar 

  • Bucolo, G., David, H.: Quantitative determination of serum triglycerides by the use of enzymes. Clin. Chem. 19, 476–482 (1972)

    Google Scholar 

  • Carlson, L. A.: Consequences of inhibition of normal and excessive lipid mobilization. Studies with nicotinic acid. Progr. Biochem. Pharmacol. 3, 151–161 (1967)

    Google Scholar 

  • Cobb, L. A., Johnson, W. P.: Hemodynamic relationships of anaerobic metabolism and plasma free fatty acids during prolonged strenuous exercise in trained and untrained subjects. J. Clin. Invest. 42, 800–810 (1963)

    Google Scholar 

  • Devlin, J., Varma, M. P., Prendergast, J.: Effects of training and exercise on growth hormone release in man. Postgrad. Med. J. 49, Suppl. 5, 144–147 (1973)

    Google Scholar 

  • Dole, V. P., Meinertz, H.: Microdetermination of long chain fatty acids in plasma and tissues. J. Biol. Chem. 235, 2595–2599 (1960)

    Google Scholar 

  • Flint, M. M., Drinkwater, B. L., Horvath, S. M.: Effects of training on women's response to submaximal exercise. Med. Sci. Sports 6, 89–94 (1974)

    Google Scholar 

  • Gollnick, P. D., Hermansen, L.: Biochemical adaptations to exercise: Anaerobic metabolism. In: Exercise and sport sciences reviews, Vol. 1 (J. H. Wilmore, ed.), pp. 1–43. New York: Academic Press 1973

    Google Scholar 

  • Gutmann, I., Wahlefeld, A. W.: L-(+)-Lactate. Determination with lactate deydrogenase and NAD. In: Methods of enzymatic analysis, (H. U. Bergmeyer, ed.), Second English edition, pp. 1464–1468. New York: Academic Press 1974

    Google Scholar 

  • Gyntelberg, F., Rennie, M. J., Hickson, R. C., Holloszy, J. O.: Effect of training on the response of plasma glucagon to exercise. J. Appl. Physiol. 43, 302–305 (1977)

    Google Scholar 

  • Hagenfeldt, L., Wahren, J.: Human forearm muscle metabolism during exercise. II. Uptake, release, and oxidation of individual FFA and glycerol. Scand. J. Clin. Lab. Invest. 21, 263–276 (1968)

    Google Scholar 

  • Hartley, L. H., Mason, J. W., Hogan, R. P., Jones, L. G., Kotchen, T. A., Mougey, E. M., Wherry, F. E., Pennington, L. L., Rickets, P. T.: Multiple hormonal responses to prolonged exercise in relation to physical training. J. Appl. Physiol. 33, 607–610 (1972)

    Google Scholar 

  • Havel, R. J., Carlson, L. A., Ekelund, L. G., Holmgren, A.: Turnover rate and oxidation of different free fatty acids in man during exercise. J. Appl. Physiol. 19, 613–618 (1964)

    Google Scholar 

  • Havel, R. J., Naimark, A., Borchgrevink, C. F.: Turnover rate and oxidation of free fatty acids of blood plasma in man during exercise: Studies during continuous infusion of palmitate-1-C-14. J. Clin. Invest. 42, 1054–1063 (1963)

    Google Scholar 

  • Holloszy, J. O., Booth, F. W.: Biochemical adaptations to endurance exercise in muscle. In: Annual review of physiology, Vol. 38 (E., Knobil, R. R. Sonnenschein and I. S. Edelman, ed.), pp. 273–291. Palo Alto: Annual Reviews 1976

    Google Scholar 

  • Johnson, R. H., Walton, J. L., Krebs, H. A., Wiliamson, D. H.: Metabolic fuels during and after severe exercise in athletes and non-athletes. Lancet 2, 452–455 (1969)

    Google Scholar 

  • Karlsson, J., Nordesjo, L. O., Saltin, B.: Muscle glycogen utilization during exercise after physical training. Acta Physiol. Scand. 90, 210–217 (1974)

    Google Scholar 

  • Kilbom, A.: Physical training in women. Scand. J. Clin. Lab. Invest. Suppl. 119, 28, 1–34 (1971)

    Google Scholar 

  • Mole, P. A., Oscai, L. B., Holloszy, J. O.: Adaptation of muscle to exercise. Increase in levels of palmityl CoA synthetase, carnitine palmityl transferase, and palmityl CoA dehydrogenase, and in the capacity of oxidize fatty acids. J. Clin. Invest. 50, 2323–2330 (1971)

    Google Scholar 

  • Pruett, D. D. R.: FFA mobilization during and after prolonged severe muscular work in men. J. Appl. Physiol. 29, 809–815 (1970)

    Google Scholar 

  • Rennie, M. J., Jennett, S., Johnson, R. H.: The metabolic effects of strenuous exercise: a comparison between untrained subjects and racing cyclists. Quart. J. Exp. Physiol. 59, 201–212 (1974)

    Google Scholar 

  • Rennie, M. J., Johnson, R. H.: Alteration of metabolic and hormonal responses to exercise by physical training. Eur. J. Appl. Physiol. 33, 215–226 (1974)

    Google Scholar 

  • Shaw, W. A. S., Issekutz, T. B., Issekutz, B.: Gluconeogenesis from glycerol at rest and during exercise in normal, diabetic, and methylprednisolone-treated dogs. Metabolism 25, 329–339 (1976)

    Google Scholar 

  • Shepherd, R. E., Sembrowich, W. L., Green, H. E., Goldnick, P. D.: Effects of physical training on control mechanisms of lipolysis in rat fat cell ghosts. J. Appl. Physiol. 42, 884–888 (1977)

    Google Scholar 

  • Winer, B. J.: Statistical principles in experimental design. Second ed., pp. 196–201, 539–448. New York: McGraw Hill 1971

    Google Scholar 

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Bransford, D.R., Howley, E.T. Effects of training on plasma FFA during exercise in women. Europ. J. Appl. Physiol. 41, 151–158 (1979). https://doi.org/10.1007/BF00430007

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