Abstract
Auditory evoked responses (AER) to trains of 6 click stimuli (1 click/sec) were studied in 9 subjects under hangover, tired control, and normal control conditions in order to find out whether the symptoms of hyperexcitability during hangover have a correlate in the characteristics of the AER. In addition, the audiograms were measured. AERs to the first click in a stimulus train were markedly smaller during hangover than in the other 2 states. The amplitude levels of the AERs during the repetition of the click stimulus were, however, similar under all three conditions. The audiograms obtained in the three states were similar except for a very slight decrease of auditory threshold sensitivity during hangover as compared with the tired control condition. The results show that the effects of hangover on AERs resemble those of alcohol intoxication. The symptoms of hyperexcitability during hangover cannot be explained in terms of increased peripheral sensitivity.
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References
Begleiter, H., Platz, A.: The effects of alcohol on the central nervous system in humans. In: Advances in experimental medicine and biology, Vol. 35, Alcohol intoxication and withdrawal—experimental studies. M. M. Gross, ed., pp. 293–343. New York: Plenum Press 1973
Begleiter, H., Porjesz, B., Yerre-Grubstein, C.: Excitability cycle of somatosensory evoked potentials during experimental alcoholization and withdrawal. Psychopharmacologia (Berl.) 37, 15–21 (1974)
Burian, K.: Evoked response audiometry (ERA)—ein objektives Hörprüfungsverfahren. HNO (Berl.) 17, 353–358 (1969)
Fruhstorfer, H., Soveri, P.: Alcohol and auditory evoked responses in man. Acta physiol. scand. 74, 26A-27A (1968)
Fruhstorfer, H., Soveri, P., JÄrvilehto, T.: Short-term habituation of the auditory evoked response in man. Electroenceph. clin. Neurophysiol. 28, 153–161 (1970a)
Fruhstorfer, H., JÄrvilehto, T., Lumio, J., Soveri, P.: Changes in spinal excitability during an auditory vertex response in man. Acta physiol. scand. 80, 42A (1970b)
Gross, M. M., Begleiter, H., Tobin, M., Kissin, B.: Changes in auditory evoked response induced by alcohol. J. nerv. ment. Dis. 143, 152–156 (1966)
JÄrvilehto, T., HÄmÄlÄinen, H.: Facilitation of electrocutaneous perception by auditory pre-stimuli. Acta psychol. fenn. III, 34 (1974)
McCallum, W. C., Walter, W. G.: The effects of attention and distraction on the contingent negative variation in normal and in neurotic subjects. Electroenceph. clin. Neurophysiol. 25, 319–329 (1968)
Mello, N. K., Mendelson, J. H.: Alterations in states of consciousness associated with chronic ingestion of alcohol. In: Neurological aspects of psychopathology. J. Zubin and C. Shagass, eds., pp. 183–229. New York: Grune and Stratton 1969
Victor, M.: The alcohol withdrawal syndrome. Postgrad. Med. 47, 68–72 (1970)
Ylikahri, R. H., Huttunen, M. O., Eriksson, C. J. P., NikkilÄ, E. A.: Metabolic studies on the pathogenesis of hangover. Europ. J. clin. Invest. 4, 93–100 (1974)
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This study was supported by the Finnish Foundation for Alcohol Studies.
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JÄrvilehto, T., Laakso, ML. & Virsu, V. Human auditory evoked responses during hangover. Psychopharmacologia 42, 173–177 (1975). https://doi.org/10.1007/BF00429549
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DOI: https://doi.org/10.1007/BF00429549