Abstract
Two experiments were performed with rats trained with either continuous reinforcement (food) or random 50% partial reinforcement for running in a straight alley. Half the rats were trained with daily injections of 0.5 mg/kg δ 9-tetrahydrocannabinol (THC) and half with vehicle injections, all animals being extinguished with vehicle injections in Expt. 1 and with THC injections in Expt. 2. The partial reinforcement acquisition effect was abolished by THC during training; the partial reinforcement extinction effect was abolished by THC either during training or during extinction. In these respects THC resembles amylobarbitone and alcohol.
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Drewnowski, A., Gray, J.A. Influence of δ 9-tetrahydrocannabinol on partial reinforcement effects. Psychopharmacologia 43, 233–237 (1975). https://doi.org/10.1007/BF00429256
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DOI: https://doi.org/10.1007/BF00429256