Skip to main content
Log in

Test for oral and postingestional factors mediating differential acceptability of morphine, methamphetamine, and chlordiazepoxide drinking solutions

  • Short Reports
  • Published:
Psychopharmacology Aims and scope Submit manuscript

Abstract

The relative degrees to which aversive oral (presumably gustatory) and postingestional variables attenuate the voluntary drinking of morphine, methamphetamine, and chlordiazepoxide solutions by rats were assessed by comparing immediate acceptability with subsequent acceptability. Results indicated that morphine solutions (0.01–0.05%) are avoided primarily because of unpalatability, while methamphetamine (0.005–0.02%) and chlordiazepoxide solutions (0.02–0.08%) are avoided primarily because of aversive postingestional effects.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Dews, P. B.: Introduction: schedule-induced polydipsia and oral intake of drugs. Pharmacol. Rev. 27, 447 (1976)

    Google Scholar 

  • Hill, S. Y., Powell, B. J.: Acquired preference for morphine but not d-amphetamine as a result of saccharine adulteration. Psychopharmacology 50, 309–312 (1976)

    Google Scholar 

  • Vogel, J. R., Nathan, B. A.: Reduction of learned taste aversions by preexposure to drugs. Psychopharmacology 49, 167–172 (1976)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wolf, G., Jacquet, Y. & Carol, M. Test for oral and postingestional factors mediating differential acceptability of morphine, methamphetamine, and chlordiazepoxide drinking solutions. Psychopharmacology 60, 101–102 (1978). https://doi.org/10.1007/BF00429186

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00429186

Key words

Navigation