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Drug-modulated behavioural responses to environmental enrichment

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Abstract

The home-cage activity of mice housed in either social or enriched sensory environments was continuously recorded for 23 days. During this period the mice were given daily injections of either strychnine, chlorpromazine, or saline. Both chlorpromazine and social rearing depressed home-cage activity. Strychnine also depressed activity, but only in the social group.

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References

  • Calhoun, W. A.: The effects of strychnine sulphate on the home cage activity and oxygen consumption in three inbred strains of mice. Psychopharmacologia (Berl.) 8, 227–234 (1965)

    Google Scholar 

  • Coyle, I. R., Singer, G.: The interactive effects of prenatal imipramine exposure and postnatal rearing conditions on behaviour and histology. Psychopharmacologia (Berl.) 44, 253–256 (1975)

    Google Scholar 

  • Eterović, V. A., Ferchmin, P. A.: Interaction of environment and injections on brain weight in rats. Dev. Psychobiol. 7, 515–517 (1974)

    Google Scholar 

  • Rosenzweig, M. R., Bennett, E. L.: Drugs modulate effects of environment on brain growth. Proc. 76th Annual Convention of the American Psychological Association (1968)

  • Rosenzweig, M. R.: Effects of environment on development of brain and of behaviour. In: The biopsychology of development, E. Tobach, L. R. Aronson, and E. Shaw, eds., pp. 303–352. New York: Academic Press 1971

    Google Scholar 

  • Scheffé, H.: The analysis of variance. New York: Wiley and Sons 1959

    Google Scholar 

  • Walsh, R. N., Cummins, R. A.: Neural responses to therapeutic environments. In: Environments as therapy for brain dysfunction, R. N. Walsh and W. T. Greenough, eds., pp. 171–200. New York: Plenum 1976

    Google Scholar 

  • Will, B. E., Rosenzweig, M. R., Bennett, E. L., Hebert, M., Moriomoto, H.: Relatively brief environmental enrichment aids recovery of learning capacity and alters brain measures after postweaning brain lesions in rats. J. Comp. Physiol. Psychol. 91, 33–50 (1977)

    Google Scholar 

  • Winer, B. J.: Statistical principles in experimental design. New York: McGraw-Hill 1962

    Google Scholar 

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Cummins, R.A., Carlyon, T.N. & Walsh, R.N. Drug-modulated behavioural responses to environmental enrichment. Psychopharmacology 58, 197–199 (1978). https://doi.org/10.1007/BF00426907

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  • DOI: https://doi.org/10.1007/BF00426907

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