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Effects of chlordiazepoxide on schedule-induced water and alcohol consumption in the squirrel monkey

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Abstract

Lever pressing of five squirrel monkeys was maintained by a 3-min fixed-interval schedule of food presentation. 3 monkeys had water concurrently available and, for a second pair of monkeys, initially water, then increasing concentrations of alcohol (1–3% v/v) were present. Substantial amounts of post-pellet drinking occurred with all five monkeys. The amount of water ingested was approximately 100 ml per session, that of 3% alcohol nearly 63 ml. For the monkeys drinking alcohol, increasing concentrations of alcohol decreased both the rate of lever pressing and the volume of fluid consumed. Chlordiazepoxide (1.0–17.0 mg/kg) produced increases in lever pressing and in the schedule-induced consumption of both 3% alcohol and water.

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Authors and Affiliations

  1. Department of Psychology, University of Maryland, USA

    James E. Barrett & Elizabeth S. Weinberg

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  1. James E. Barrett
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  2. Elizabeth S. Weinberg
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Barrett, J.E., Weinberg, E.S. Effects of chlordiazepoxide on schedule-induced water and alcohol consumption in the squirrel monkey. Psychopharmacologia 40, 319–328 (1975). https://doi.org/10.1007/BF00421470

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  • DOI: https://doi.org/10.1007/BF00421470

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