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Investigations on laser coagulated rat eyes by fluorescence angiography and microscopy

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Summary

Laser coagulation using 50 and 100 mW of power, a spot of 50 microns and an exposure time of 0,2 seconds were performed on rat eye fundi. We observed the effects which were produced in the retina and choroid utilizing both fluorescence photomicroscopy with incident excitation light and fluorescence angiography. No distinct differences were noticed between the effects produced by 50 and by 100 mW. Both energies damaged choroid and retina, especially the outer part of the retina. Moreover, fluorescein angiography within 24 hours gave us effective information for estimating the applied laser effect.

Zusammenfassung

An Rattenfundi wurden Laser-Koagulationen mit einer Intensität von 50 und 100 mW, einem Spot von 50 Mikron und einer Belichtungszeit von 0,2 sec durchgeführt. Die erzielten Effekte wurden sowohl mit Fluorescenzenzangiographie als auch Fluorescenzphotomicroscopie mit Auflicht beobachtet und dargestellt. Es wurden keine wesentlichen Unterschiede zwischen den mit 50 mW und 100 mW verursachten Effekten beobachtet. Mit beiden Energien wurden Netzhaut und Aderhaut geschädigt, insbesondere die äußeren Schichten der Netzhaut. Die 24 Stunden nach der Laser-Koagulation durchgeführte Eluorescenzangiographie vermittelte wichtige Informationen für die Auswertung der Lasereffekte.

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References

  1. Aoki, A.: Fluorescein angiographic and electron microscopic findings of the retinas of pigmented rabbits immediately after ruby laser photocoagulation. Folia ophthal. Jap. 23, 707–720 (1972)

    Google Scholar 

  2. Appel, D. J., Goldberg, M. F., Wyhinny, G.: Histopathology and ultrastructure of the argon laser lesion in human retinal and choroidal vasculature. Amer. J. Ophthal. 75, 595–609 (1973)

    Google Scholar 

  3. Baurmann, H.: Grundlagen der Fluorescenzangiographie des Augenhintergrundes. Advanc. Ophthal. 24, 204–263 (1971)

    Google Scholar 

  4. Hosoya, S.: Ophthalmoscopic and fluorescein angiographic and histological study of chorioretinal lesion produced by ruby laser on rabbit. Acta Soc. ophthal. Jap. 75, 2127–2136 (1971)

    Google Scholar 

  5. Mizuno, K., Sasaki, K., Otsuki, K.: Histochemical identification of fluorescein in ocular tissue. Proceed. ISFA Tokyo 1972, Igaku Shoin, p. 221–225 (1974)

  6. Ota, M.: Fluorescein microscopic studies of experimental light coagulation in the rabbit eye. Folia Ophthal. Jap. 24, 499–504 (1973)

    Google Scholar 

  7. Sasaki, K., Otsuki, K., Mizuno, K.: Histochemical identification of sodium fluorescein in normal retina. Jap. J. ophthal. 17, 323–334 (1973)

    Google Scholar 

  8. Tsukahara, I., Ota, M.: Angiographic-histologic study on the location of sodium fluorescein in the fundus. Proceed. ISFA Tokyo 1972, Igaku Shoin, p. 230–234 (1974)

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This investigation was in part reported on the Symposium “Laser and Eye”, Albi (France), May 20 th–24 th, 1974.

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Baurmann, H., Sasaki, K. & Chioralia, G. Investigations on laser coagulated rat eyes by fluorescence angiography and microscopy. Albrecht von Graefes Arch. Klin. Ophthalmol. 193, 245–252 (1975). https://doi.org/10.1007/BF00417573

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  • DOI: https://doi.org/10.1007/BF00417573

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