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Studies on the mechanism of action of sulfanilamide on mycelial felts of Rhizoctonia solani

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Summary

Sulfanilamide induced strong inhibitory effects on the growth, respiration and carbohydrate synthesis by mycelial felts of Rhizoctonia solani. The possible reasons for such inhibitory effects are discussed.

The inhibitory effects of sulfanilamide were almost completely alleviated by the inclusion of p-aminobenzoic (PABA) acid in the culture medium of the fungal mats.

R. solani normally produces certain amounts of PABA and its growth and metabolism is inhibited in presence of excess of it.

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References

  • Audus, L. J., and J. H. Quastel: The growth inhibitory activity of the sulfonamides and plant growth-substances, and the effects thereon of p-aminobenzoic acid. Ann. Bot. 12, 27 (1948).

    Google Scholar 

  • Boll, W. G.: Inhibition of excised tomato roots by sulfanilamide and its reversal by p-aminobenzoic acid and N-pteroylglutamic acid. Plant Physiol. 30, 161 (1955).

    Google Scholar 

  • Bonner, J.: A reversible growth inhibition of isolated tomato roots. Proc. nat. Acad. Sci. (Wash.) 28, 321 (1942).

    Google Scholar 

  • Dimond, N. S.: p-Aminobenzoic acid prevents the growth inhibitory action of sulfanilamide. Science 94, 420 (1941).

    Google Scholar 

  • Emerson, S.: Growth responses of a “sulfonamide-requiring” mutant strain of Neurospora. J. Bact. 54, 195 (1947).

    Google Scholar 

  • Hazard, R.: p-Aminobenzoic acid as an antagonist of the inhibiting action of sulfanilamide on germination and growth of flax seeds. C. R. Soc. Biol. (Paris) 138, 972 (1944).

    Google Scholar 

  • Knight, B. C. J. G.: Growth factors in microbiology. Vitam. and Horm. 3, 105 (1945).

    Google Scholar 

  • Rubbo, S. D., and J. M. Gillespie: Para-aminobenzoic acid as a bacterial growth factor. Nature (Lond.) 146, 838 (1940).

    Google Scholar 

  • Sevag, M. G.: Enzyme problems in relation to chemotherapy, adaptation, mutations, resistance and immunity. Advanc. Enzymol. 6, 33 (1946).

    Google Scholar 

  • Tatum, E. L., and G. W. Beadle: Genetic control of biochemical reactions in Neurospora: an “Aminobenzoic-less” mutant. Proc. nat. Acad. Sci. (Wash.) 28, 234 (1942).

    Google Scholar 

  • Tolba, M. K., and A. M. Salama: Effect of age of mycelial felts of Rhizoctonia solani on their growth, respiration, and absorption and utilisation of sucrose (in press) (1961).

  • Tuber, H., and S. Lauffer: A colour test for p-aminobenzoic acid, the chromotrichia factor. J. Amer. chem. Soc. 63, 1488 (1941).

    Google Scholar 

  • Woods, D. D.: The relation of p-aminobenzoic acid to the mechanism of the action of sulfanilamide. Brit. J. exp. Path. 21, 74 (1940).

    Google Scholar 

  • Wyss, O., K. K. Grubaugh and F. C. Schmelkes: Nonspecificity of sulfonamides. Proc. Soc. exp. Biol. (N. Y.) 49, 618 (1942).

    Google Scholar 

  • Zalokar, M.: p-Aminobenzoic acid requirement of the “sulfonamide-requiring” mutant strain of Neurospora. Proc. nat. Acad. Sci. (Wash.) 34, 32 (1948).

    Google Scholar 

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Authors and Affiliations

  1. Botany Department, Faculty of Science, University of Cairo, Egypt, UAR

    M. K. Tolba & A. M. Salama

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  1. M. K. Tolba
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  2. A. M. Salama
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Tolba, M.K., Salama, A.M. Studies on the mechanism of action of sulfanilamide on mycelial felts of Rhizoctonia solani. Archiv für Mikrobiologie 43, 336–348 (1962). https://doi.org/10.1007/BF00408677

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  • DOI: https://doi.org/10.1007/BF00408677

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