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Beta-ray treatment of malignant epibulbar melanoma

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Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Aims and scope Submit manuscript

Summary

Sixty-eight patients suffering from conjunctival melanoma were treated by beta-irradiation. The dose given ranged between 15,000 and 20,000 rd at the tumor surface. In 75% the therapy was successful. In 67,4% the melanoma could be cured by beta-irradiation alone with a follow-up period between three and ten years. The lethality rate from proven metastases was only 6.2%. The regression time after beta-therapy, as a rule, exceeded several months. Beta-rays can be used either primarily or after tumor excision. Care should be taken that the applicator covers all the tissue containing tumor cells.

Zusammenfassung

68 Patienten mit einem Bindehautmelanom wurden mit Betabestrahlung behandelt. Die applizierte Dosis betrug 15,000 bis 20,000 rd an der Tumoroberfläche. In 75% war die Behandlung erfolgreich. In 67,4% konnte das Melanom allein durch die Betabestrahlung bei einer Nachkontrollzeit zwischen 3 und 10 Jahren geheilt werden. Die Letalitätsrate betrug 6,1%. Die Rückbildungszeit nach der Betastrahlung erforderte in der Regel mehrere Monate. Die Betabestrahlung kann entweder allein oder nach der Tumorexcision durchgeführt werden. Es muß dabei sorgsam darauf geachtet werden, daß der Applikator das vom Tumor befallene Gewebe vollständig bedeckt.

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Authors and Affiliations

  1. Department of Ophthalmology, Städtisches Klinikum Berlin-Buch, Karowerstr. 11, DDR-1115, Berlin, Germany

    P. K. Lommatzsch

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  1. P. K. Lommatzsch
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Lommatzsch, P.K. Beta-ray treatment of malignant epibulbar melanoma. Albrecht von Graefes Arch. Klin. Ophthalmol. 209, 111–124 (1978). https://doi.org/10.1007/BF00407844

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