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Radiological criteria of industrial fluorosis

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Abstract

The bone radiographs of 43 potroom workers in an aluminium factory, on whom the diagnosis of industrial fluorosis had been confirmed by bone biopsy, are compared with radiographs from 18 control subjects. A higher frequency of ossification of ligament, tendon, and muscle attachments is observed among the fluoride exposed subjects. These changes increase with the bone fluoride content.

The presence of hyperostosis is an important aid in the diagnosis of skeletal fluorosis. However, this radiological sign has to be complemented by clinical data and estimation of the concentration of urinary fluoride. Final confirmation of the diagnosis is obtained by bone biopsy.

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References

  1. Barnett, E., Nordin, B.E.C.: The radiological diagnosis of osteoporosis: A new approach. Clin. Radiol. 11, 166 (1960)

    Google Scholar 

  2. Baud, C.A.: Radiographies et microradiographies osseuses quantitatives. Praxis 46, 329 (1957)

    Google Scholar 

  3. Baud, C.A., Lagier, R., Boivin, G., Boillat, M.A.: Value of the bone biopsy in the diagnosis of industrial fluorosis. Virchows Arch. (Pathol. Anat.) 380, 283 (1978)

    Google Scholar 

  4. Boillat, M.A.: Industrial fluorosis: Correlations and tentative conclusions. In: Symposium CEMO II, Fluoride and bone, B. Courvoisier, A. Donath, C.A. Baud, Ed., p. 180. Geneva Médecine et Hygiéne 1978

    Google Scholar 

  5. Boillat, M.A., Baud, C.A., Lagier, R., Donath, A., Dettwiler, W., Courvoisier, B.: Fluorose industrielle. Schweiz. Med. Wochenschr. 106, 1842 (1976)

    Google Scholar 

  6. Boillat, M.A., Baud, C.A., Lagier, R., Garcia, J., Rey, P., Bang, S., Boivin, C., Demeurisse, C., Gössi, M., Tochon-Danguy, H.J., Very, J.M., Burckhardt, P., Voinier, B., Donath, A., Courvoisier, B.: Fluorose industrielle. Etude multidisciplinaire de 43 ouvriers de l'industrie de l'aluminium. Schweiz. Med. Wochenschr. (Suppl) 109, Fasc. 19, Suppl. 8 (1979)

  7. Boillat, M. A., Garcia, J., Dettwiler, W., Burckhardt, P., Courvoisier, B.: Clinical aspects of industrial fluorosis. In: Symposium CEMO II, Fluoride and bone, B. Courvoisier, A. Donath, C. A. Baud, Ed., p. 155. Geneva: Médecine et Hygiēne 1978

    Google Scholar 

  8. Boillat, M.A., Rouget, A., Curati, W., Dettwiler, W., Maillard, J.M., May, P., Demeurisse, C.: Quelques aspects de la fluorose industrielle en Suisse. II. Radiologie et fluor osseux. Arch. Mal. Prof. 36, 412 (1975)

    Google Scholar 

  9. Boulet, P., Serre, H., Mirouze, J.: Le rachis diabétique. Sem. Hôp. Paris 30, 2392 (1954)

    Google Scholar 

  10. Dequeker, J.: Bone loss in normal and pathological conditions. Leuven: Leuven University Press 1972

    Google Scholar 

  11. Derryberry, O.M., Batholomew, M.D., Fleming, R.B.L.: Fluoride exposure and worker health. Arch. Environ. Health. 6, 503 (1963)

    Google Scholar 

  12. Dinman, B.D., Elder, M.J., Bonney, T.B., Bovard, P.G., Colwell, M.O.: A 15-year retrospective study of fluoride excretion and bony radiopacity among aluminium smelter workers — part 4. J. Occup. Med. 18, 21 (1976)

    Google Scholar 

  13. Forestier, J., Lagier, R.: Ankylosing hyperostosis of the spine. Clin. Orthop. 74, 65 (1971)

    Google Scholar 

  14. Forestier, J., Rotes Querol, J.: Senile ankylosing hyperostosis of the spine. Ann. Rheum. Dis. 9, 321 (1950)

    Google Scholar 

  15. Franke, J., Auermann, E.: Die Bedeutung der Beckenkammpunktion mit histologischer und mikroanalytischer Untersuchung des gewonnenen Knochenmaterials bei der Diagnostik der Fluorose. Int. Arch. Occup. Environ. Health 29, 85 (1972)

    Google Scholar 

  16. Hajkova, Z., Streda, A., Skrha, F.: Hyperostotic spondylosis and diabetes mellitus. Ann. Rheum. Dis. 24, 536 (1965)

    Google Scholar 

  17. Hodge, H.C., Smith, F.A.: Occupational fluoride exposure. J. Occup. Med. 19, 12, (1977)

    Google Scholar 

  18. Johnson, L.C.: Histogenesis and mechanisms in the development of osteofluorosis. In: Fluorine chemistry. J.H. Simons, Ed. p. 424. New York, London: Academic Press 1965

    Google Scholar 

  19. Jolly, S.S.: Hydric fluorosis in Punjab (India). In: Fluoride in medicine. T.L. Vischer, Ed., p. 106. Stuttgart, Wien, Bern: Hans Huber 1970

    Google Scholar 

  20. Julkunen, H., Kärävä, R., Viljanen, V.: Hyperostosis of the spine in diabetes mellitus and acromegaly. Diabetologia 2, 123 (1966)

    Google Scholar 

  21. Kaltreider, N.L., Elder, M.J., Cralley, L.V., Colwell, M.O.: Health survey of aluminium workers with special reference to fluoride exposure. J. Occup. Med. 14, 531 (1972)

    Google Scholar 

  22. Lagier, R., Meinecke, R.: Hyperostose de la crête iliaque. Rev. Rhum. Mal. Ostéoartic. 44, 131 (1977)

    Google Scholar 

  23. McCann, H.C.: Determination of fluoride in mineralized tissues using the fluoride ion electrode. Arch. Oral Biol. 13, 475 (1968)

    Google Scholar 

  24. Manigand, G.: L'ostéose fluorée. Rev. Praticien 21, 3467 (1971)

    Google Scholar 

  25. Moller, P.F., Gudjonsson, S.V.: Massive fluorosis of bones and ligaments. Acta Radiol. 13, 269 (1932)

    Google Scholar 

  26. National Institute for Occupational Safety and Health: Criteria for a recommended standard ... occupational exposure to inorganic fluorides. HEW Publication No. (NIOSH) 76-103. Washington: U.S. Government Printing Office 1976

    Google Scholar 

  27. Resnick, D., Shaul, S.R., Robins, J.M.: Diffuse idiopathic skeletal hyperostosis (DISH): Forestier's disease with extraspinal manifestation. Radiology 115, 513 (1975)

    Google Scholar 

  28. Rey, P., Voinier, B., Boillat, M.A.: Selection of relevant variables for the diagnosis of industrial fluorosis. In: Symposium CEMO II, Fluoride and bone, B. Courvoisier, A. Donath, C.A. Baud, Ed., p. 176. Geneva: Medecine et Hygiēne 1978

    Google Scholar 

  29. Roholm, K.: Fluorine intoxication, Nyt Nordisk, Ed. London: H.K. Lewis 1937

    Google Scholar 

  30. Schoen, D., Eggstein, M., Vogt, W.: Ist die hyperostotische Spondylosis deformans eine diabetische Osteopathie? Fortschr. Röntgenstr. 110, 524 (1969)

    Google Scholar 

  31. Vischer, T.L., Bernheim, C., Guerdjikoff, C., Wettstein, P., Lagier, R.: Industrial fluorosis. In: Fluoride in medicine, T.L. Vischer, Ed., p. 96. Bern, Stuttgart, Wien: Hans Huber 1970

    Google Scholar 

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Boillat, M.A., Garcia, J. & Velebit, L. Radiological criteria of industrial fluorosis. Skeletal Radiol. 5, 161–165 (1980). https://doi.org/10.1007/BF00347257

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