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Postpartum CT examination of the heads of full term infants

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Summary

Intracranial hemorrhage and decreased density of the cerebral parenchyma were the major findings on CT of 150 full term newborns in the first week of life. Clinically silent hemorrhage was rare. All neonates with severe intracranial bleeding had neurological abnormalities. A correlation was not found between hemorrhage and the mode of delivery. The site of hemorrhage has an important bearing on brain development. Periventricular hypodensity is an ambiguous finding which should be interpreted in conjunction with the clinical findings.

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References

  1. Arimitsu, T., Di Chiro, G., Brooks, R. A., Smith, P. B.: Whitegray matter differentiation in computed tomography. J. Comput. Assist. Tomogr. 1, 437–442 (1977)

    Google Scholar 

  2. Banker, B. Q., Laroche, J. C.: Periventricular leukomalacia of infancy: A form of neonatal anoxic encephalopathy. Arch. Neurol. 7, 386–410 (1962)

    Google Scholar 

  3. Bosch, E. P., Cancilla, P. A., Cornell, S. H.: Computerized tomography in progressive multifocal leukoencephalopathy. Arch. Neurol. 33, 216 (1976)

    Google Scholar 

  4. Brand, M., Brockerhoff, P., Ludwig, B.: Hirnblutungen bei Neugeborenen: Untersuchungen zur Häufigkeit in Abhängigkeit vom Entbindungsmodus mit Hilfe der Computertomographie. 76. Tagung der Deutschen Gesellschaft für Kinderheilkunde, Karlsruhe 17.–19.9.79

  5. Brand, M., Ludwig, B., Brockerhoff, P., Spranger, J.: Dicfiteminderung im CT des Neugeborenen und ihre Bedeutung für die Langzeitprognose. 6. Symposium über pädiatrische Intensivmedizin, Frankfurt/Main, 26.–27.4.1980. Stuttgart: Thieme (in press)

  6. Brand, M., Ludwig, B., Brockerhoff, P., Spranger, J.: Computertomographisch gesicherte intracranielle Blutungen beim Neugeborenen und ihre Bedeutung für die Langzeitprognose. 29. Tagung der Süddeutschen Kinderärzte, Kaiserslautern, 17.–18.5.1980

  7. Burstein, J., Papile, L., Burstein, R.: Subependymal germinal matrix and intraventricular hemorrhage in premature infants: Diagnosis by CT. Am. J. Roentgenol. 128, 971–976 (1977)

    Google Scholar 

  8. Burstein, J., Papile, L., Burstein, R.: Intraventricular hemorrhage and hydrocephalus in premature newborns: A prospective study with CT. Am. J. Roentgenol. 132, 631–635 (1979)

    Google Scholar 

  9. Cartwright, G. W., Culbertson, K., Schreiner, R. L., Garg, B. P.: Changes in clinical presentation of term infants with intracranial hemorrhage. Dev. Med. Child. Neurol. 21, 730–737 (1979)

    Google Scholar 

  10. Chaplin, E. R., Goldstein, G. W., Norman, D.: Neonatal seizures, intracerebral hematoma, and subarachnoid hemorrhage in full term infants. Pediatrics 63, 812–815 (1979)

    Google Scholar 

  11. Deonna, T., Payot, M., Probst, A., Prod'hom, L. -S.: Neonatal intracranial hemorrhage in premature infants. Pediatrics 56, 1056–1064 (1975)

    Google Scholar 

  12. DeReuck, J., Chattha, A. S., Richardson, E. P.: Pathogenesis and evolution of periventricular leukomalacia in infancy. Arch. Neurol. 27, 229–236 (1972)

    Google Scholar 

  13. Di Chiro, G., Arimitsu, T., Pellock, J. M., Landes, R. D.: Periventricular leukomalacia related to neonatal anoxia: Recognition by computed tomography. J. Comput. Assist. Tomogt. 2, 352–355 (1978)

    Google Scholar 

  14. Donat, J. F., Okazaki, H., Kleinberg, F., Reagan, T. J.: Intraventricular hemorrhages in full-term and premature infants. Mayo Clin. Proc. 53, 437–441 (1978)

    Google Scholar 

  15. Eiben, R. M., Di Chiro, G.: Computer assisted tomography in adrenoleukodystrophy. J. Comput. Assist. Tomogr. 1, 303–314 (1977)

    Google Scholar 

  16. Flechsig, P.: Anatomie des menschlichen Gehirns und Rükkenmarks auf myelogenetischer Grundlage. Leipzig: Thieme 1920

    Google Scholar 

  17. Flodmark, C. O., Fitzhardinge, P. M., Fitz, C. R., Harwood-Nash D. C. F.: Prognostic value of neonatal CT: eighteen months followup of children with perinatal asphyxia. The American Society of Neuroradiology, Eighteenth Annual Meeting, Los Angeles, 16.–21.3.1980

  18. Friede, R. L.: Developmental neuropathology. Berlin Heidelberg, New York: Springer 1976, pp 1–37

    Google Scholar 

  19. Garrick, R., Gomez, M. R., Houser, O. W.: Demyelinisation of the brain in tuberous sclerosis. Computed tomography evidence. Mayo Clin. Proc. 54, 685–689 (1979)

    Google Scholar 

  20. Gruenwald, P.: Subependymal cerebral hemorrhage in premature infants, and its relation to various injurious influences at birth. Am. J. Obstet. Gynecol. 61, 1285–1292 (1951)

    Google Scholar 

  21. Grunnet, M. L., Curless, R. G., Bray, D. F., Jung, A. L.: Brain changes in newborns from an intensive care unit. Dev. Med. Child. Neurol. 16, 320–328 (1974)

    Google Scholar 

  22. Harcke, H. T., Naege, R. I., Storch, A., Blanc, W. A.: Perinatal cerebral intraventricular hemorrhage. J. Pediatr. 80, 37–42 (1972)

    Google Scholar 

  23. Kotlarek, F., Zeumer, H.: Computertomographische Detailhinweise bei neurologischen Funktionsstörungen des ZNS in der Neugeborenenperiode. Monatsschr. Kinderheilk. 128, 428–431 (1980)

    Google Scholar 

  24. Krishnamoorthy, K. S., Fernandez, R. A., Momose, K. J., DeLong, G. R., Moylan, F. M. B., Todres, J. D., Shannon, D. C.: Evaluation of neonatal intracranial hemorrhage by computerized tomography. Pediatrics 59, 165–172 (1977)

    Google Scholar 

  25. Laroche, J. C.: Developmental pathology of the neonate. Amsterdam: Excerpta medica 1977

    Google Scholar 

  26. Lee, B. C. P., Grassi, A. E., Schechner, S., Auld, P. A. M.: Neonatal intraventricular hemorrhage: A serial computed tomography study. J. Comput. Assist. Tomogr. 3, 483–490 (1979)

    Google Scholar 

  27. Leech, R. W., Alvord, E. C.: Morphologic variations in periventricular leukomalacia. Am. J. Pathol. 74, 591–602 (1974)

    Google Scholar 

  28. Leech, R. W., Kohnen, P.: Subependymal and intraventricular hemorrhages in the newborn. Am. J. Pathol. 77, 465–476 (1974)

    Google Scholar 

  29. Ludwig, B., Wende, S., Brand, M., Brockerhoff, P.: Postpartal cranial CT examination of full term infants. The American Society of Neuroradiology. Eighteenth Annual Meeting, Los Angeles, 16.–21.3.1980

  30. New, P. F. J., Aronow, S.: Attenuation measurements of whole blood and blood fractions in computed tomography. Radiology 121, 635–640 (1976)

    Google Scholar 

  31. Palma, P. A., Miner, M. E., Morris, F. H., Adcock III, E. W., Denson, S. E.: Intraventricular hemorrhage in the neonate born at term. Am. J. Dis. Child. 133, 941–944 (1979)

    Google Scholar 

  32. Pape, K. E., Wigglesworth, J. S.: Hemorrhage, ischaemia and the perinatal brain. London: Heinemann 1979

    Google Scholar 

  33. Papile, L., Burstein, J., Burstein, R., Koffler, H.: Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with birth weights less than 1.500 gm. J. Pediatr. 92, 529–534 (1978)

    Google Scholar 

  34. Pasquini, U., Bronzini, M., Gozzoli, E., Mancini, P., Menichelli, F., Salvolini, U.: Periventricular hypodensity in hydrocephalus: a clinicoradiological and mathematical analysis using computed tomography. J. Comput. Assist. Tomogr. 1, 443–448 (1977)

    Google Scholar 

  35. Pevsner, P. H., Garcia-Bunuel, R., Leeds, N., Finkelstein, M.: Subependymal and intraventricular hemorrhage in neonates. Radiology 119, 111–114 (1976)

    Google Scholar 

  36. Rumack, C. M., McDonald, M. M., O'Meara, O. P., Sanders, B. B., Rudikoff, J. C.: CT detection and course of intracranial hemorrhage in premature infants. Am. J. Roentgenol. 131, 493–497 (1978)

    Google Scholar 

  37. Serfontein, G. L., Rom, S., Stein, S.: Posterior fossa subdural hemorrhage in the newborn. Pediatrics 65, 40–43 (1980)

    Google Scholar 

  38. Scott, W. R., New, P. F. J., Davis, K. R., Schnur, J. A.: Computerized axial tomography of intracerebral and intraventricular hemorrhage. Radiology 112, 73–80 (1974)

    Google Scholar 

  39. Towbin, A.: Cerebral intraventricular hemorrhage and subependymal matrix infarction in the fetus and premature newborn. Am. J. Pathol. 52, 121–140 (1968)

    Google Scholar 

  40. Towbin, A.: Cerebral hypoxic damage in fetus and premature newborn: Basic patterns and their clinical significance. Arch. Neurol. 20, 35–43 (1969)

    Google Scholar 

  41. Towbin, A.: Mental retardation due to germinal matrix infarction. Science 164, 156–161 (1969)

    Google Scholar 

  42. Tsiantos, A., Victorin, L., Reiler, J. P., Dyer, N., Sundell, H., Brill, A. B., Stahlmann, M.: Intracranial hemorrhage in the prematurely born infant: timing of clots and evaluation of clinical signs and symptoms. J. Pediatr. 85, 854–859 (1974)

    Google Scholar 

  43. Valdes-Dapena, M. A., Arey, J. B.: The causes of neonatal mortality: an analysis of 501 autopsies in newborn infants. J. Pediatr. 77, 366 (1970)

    Google Scholar 

  44. Volpe, J.: Neonatal intracranial hemorrhage: iatrogenic etiology? N. Engl. J. Med. 291, 43 (1974)

    Google Scholar 

  45. Volpe, J.: Neonatal intracranial hemorrhage-pathophysiology, neuropathology, and clinical features. Clin. Perinatol. 4, 77–102 (1977)

    Google Scholar 

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Authors and Affiliations

  1. Department of Neuroradiology, University Hospital Mainz, RFG

    B. Ludwig

  2. Department of Pediatrics, University Hospital Mainz, FRG

    M. Brand

  3. Department of Obstetrics and Gynecology, University Hospital Mainz, FRG

    P. Brockerhoff

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  1. B. Ludwig
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  2. M. Brand
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  3. P. Brockerhoff
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Ludwig, B., Brand, M. & Brockerhoff, P. Postpartum CT examination of the heads of full term infants. Neuroradiology 20, 145–154 (1980). https://doi.org/10.1007/BF00341779

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