Skip to main content
Log in

Ribonukleinsäure-Synthese der Riesenchromosomen

Autoradiographische Untersuchungen an Chironomus tentans

  • Published:
Chromosoma Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  • Allfrey, V. G., V. C. Littau and A. E. Mirsky: On the role of histones in regulating ribonucleic acid synthesis in the cell nucleus. Proc. nat. Acad. Sci. (Wash.) 49, 414–421 (1963).

    Google Scholar 

  • Amano, M., and C. P. Leblond: Comparison of the specific activity time curves of ribonucleic acid in chromatin, nucleolus and cytoplasm. Exp. Cell Res. 20, 250–253 (1960).

    Google Scholar 

  • Bauer, H.: Der Aufbau der Chromosomen aus den Speicheldrüsen von Chironomus Thummi Kieff. Z. Zellforsch. 23, 280–313 (1935); - Chromosomen und Systematik bei. Chironomiden. Arch. Hydrobiol. 40, 994–1008 (1945).

    Google Scholar 

  • —, u. W. Beermann: Die Polytänie der Riesenchromosomen. Chromosoma (Berl.) 4, 630–648 (1952).

    Google Scholar 

  • —, u. N. W. Timoféeff-Ressovsky: Vererbung und Vererbungscytologie von Drosophila im Schulversuch. Biologe 8, 324–335 (1939).

    Google Scholar 

  • Becker, H. J.: Die Puffs der Speicheldrüsenchromosomen von Drosophila melanogaster. I. Mitt.: Beobachtungen zum Verhalten des Puffmusters im Normalstamm und bei zwei Mutanten, giant und lethal-giant-larvae. Chromosoma (Berl.) 10, 654–678 (1059).

    Google Scholar 

  • Beermann, W.: Chromosomenkonstanz und spezifische Modifikationen der Chromosomenstruktur in der Entwicklung und Organdifferenzierung von Chironomus tentans. Chromosoma (Berl.) 5, 139–198 (1952); - Cytologische Analyse eines Camptochironomus-Artbastards. I. Kreuzungsergebnisse und die Evolution des Karyotypus. Chromosoma (Berl.) 7, 198–259 (1955) ; - Chromosomal differentiation in insects. In: Developmental Cytology, edit. D. Rudnick. Ronald, New York 1959; - Der Nukleolus als lebenswichtiger Bestandteil des Zellkerns. Chromosoma (Berl.) 11, 263–296 (1960); - Ein Balbianiring als Locus einer Speicheldrüsenmutation. Chromosoma (Berl.) 12, 1–25 (1961 a); - Genaktivität und Genaktivierung in Riesenchromosomen. Verh. dtsch. zool. Ges. Saarbrücken 1961, 44–75 (1961b).

    Google Scholar 

  • —, and G. F. Bahr: The submicroscopic structure of the Balbianiring. Exp. Cell Res. 6, 195–201 (1954).

    Google Scholar 

  • Bonner, J., and R.-c.C. Huang:Properties of chromosomal nucleohistone. J. molec. Biol. 6, 169–174 (1963).

    Google Scholar 

  • Boyd, G. A.: Autoradiography in biology and medicine. New York: Academic Press 1955.

    Google Scholar 

  • Brenner, S.: On the impossibility of all overlapping triplet codes in information transfer from nucleic acid to protein. Proc. nat. Acad. Sci. (Wash.) 43, 687–694 (1957).

    Google Scholar 

  • F. Jacob and M. Meselson: An unstable intermediate carrying information from genes to ribosomes for protein synthesis. Nature (Lond.) 190, 576–581 (1961).

    Google Scholar 

  • Caspersson, T.: Studien über den Eiweißumsatz der Zelle. Naturwissenschaften 29, 33–43 (1941).

    Google Scholar 

  • Clever, U.: Genaktivitäten in den Riesenchromosomen von Chironomus tentans und die Beziehungen zur Entwicklung. I. Genaktivierung durch Ecdyson. Chromosoma (Berl.) 12, 607–675 (1961); - Genaktivitäten in den Riesenchromosomen von Chironomus tentans und ihre Beziehungen zur Entwicklung. II. Das Verhalten der Puffs während des letzten Larvenstadiums mit der Puppenhäutung. Chromosoma (Berl.) 13, 385–436 (1962) ; - Von der Ecdysonkonzentration abhängige Genaktivitätsmuster in den Speicheldrüsenchromosomen von Chironomus tentans. Develop. Biol. 6, 73–98 (1963).

    Google Scholar 

  • —, u. P. Karlson: Induktion von Puff-Veränderungen in den Speicheldrüsenchromosomen von Chironomus tentans durch Ecdyson. Exp. Cell Res. 20, 623–626 (1960).

    Google Scholar 

  • Doniach, L, and S. R. Pelc: Autoradiographic technique. Brit. J. Radiol. 23, 184–192 (1950).

    Google Scholar 

  • Dounce, A. L.: Nucleic acid template hypotheses. Nature (Lond.) 172, 541(1953).

    Google Scholar 

  • Dutt, M. K., and B. P. Kaufmann: Degradational action of deoxyribonuclease on unfixed chromosomes of Drosophila and grasshoppers. Nucleus 2, 85–98 (1959).

    Google Scholar 

  • Edström, J.-E.: Extraction, hydrolysis and electrophoretic analysis of ribonucleic acid from microscopic tissue units (microphoresis). J. biophys. biochem. Cytol. 8, 39–46 (1960); - Composition of ribonucleic acid from various parts of spider oocytes. J. biophys. biochem. Cytol. 8, 47–51 (1960).

    Google Scholar 

  • —, and W. Beermann: The base composition of nucleic acids in chromosomes, puffs, nucleoli, and cytoplasm of Chironomus salivary gland cells. J. biophys. biochem. Cytol. 14, 371–380 (1962).

    Google Scholar 

  • W. Grampp and N. Schor: The intracellular distribution and heterogeneity of ribonucleic acid in starfish oocytes. J. biophys. biochem. Cytol. 11, 549–557 (1961).

    Google Scholar 

  • Flax, M. H., and M. H. Himes: Microspectrophotometric analysis of metachromatic staining of nucleic acids. Physiol. Zool. 25, 297–311 (1952).

    Google Scholar 

  • Gall, J. G., and H. G. Callan: H3-uridine incorporation in lampbrush chromosomes. Proc. nat. Acad. Sci. (Wash.) 48, 562–570 (1962).

    Google Scholar 

  • Gamov, G.: Possible relation between deoxyribonueleic acid and protein structures. Nature (Lond.) 173, 318 (1954).

    Google Scholar 

  • Goldstein, L., and J. Micou: On the primary site of nuclear RNA synthesis. J. biophys. biochem. Cytol. 6, 301–303 (1959).

    Google Scholar 

  • —, and W. Plaut: Direct evidence for nuclear synthesis of cytoplasmic ribose nucleic acid. Proc. nat. Acad. Sci. (Wash.) 41, 874–880 (1955).

    Google Scholar 

  • Goodman, H. M., and A. Rich: Formation of a DNA-soluble RNA hybrid and its relation to the origin, evolution, and degeneracy of soluble RNA. Proc. nat. Acad. Sci. (Wash.) 48, 2101–2109 (1962).

    Google Scholar 

  • Gros, F., H. Hiatt, W. Gilbert, C. G. Kurland, R. W. Risebrough and J. D. Watson: Unstable ribonucleic acid revealed by pulse labelling of Escherichia coli. Nature (Lond.) 190, 581–585 (1961).

    Google Scholar 

  • Hall, B. D., and S. Spiegelman: Sequence complementarity of T2-DNA of T2-specific RNA. Proc. nat. Acad. Sci. (Wash.) 47, 137–146 (1961).

    Google Scholar 

  • Hayashi, M., and S. Spiegelman: The selective synthesis of informational RNA in bacteria. Proc. nat. Acad. Sci. (Wash.) 47, 1564–1580 (1961).

    Google Scholar 

  • Heitz, E., u. H. Bauer: Beweise für die Chromosomennatur der Kernschleifen in den Knäuelkernen von Bibio hortulanus L. Z. Zellforsch. 17, 67–82 (1933).

    Google Scholar 

  • Hiatt, H. H.: A rapidly labeled RNA in rat liver nuclei. J. molec. Biol. 5, 217–229 (1962).

    Google Scholar 

  • Hill, D. K.: Resolving power with tritium autoradiographs. Nature (Lond.) 194, 821–832 (1962).

    Google Scholar 

  • Hoagland, M. B., P. C. Zamecnik and M. L. Stephenson: Intermediate reactions in protein biosynthesis. Biochim. biophys. Acta (Amst.) 24, 215–216 (1957).

    Google Scholar 

  • M. L. Stephenson, J. F. Scott, L. I. Hecht and P. C. Zamecnik: A soluble ribonueleic acid intermediate in protein synthesis. J. biol. Chem. 231, 241–257 (1958).

    Google Scholar 

  • Huang, R.-c.C., and J. Bonner: Histone, a suppressor of chromosomal RNA synthesis. Proc. nat. Acad. Sci. (Wash.) 48, 1216–1222 (1962).

    Google Scholar 

  • Hughes, W. L.: Autoradiography with tritium. Proc. Symp. on Tritium in Tracer Appl. New England Nuclear Corp. 1957.

  • Ishihama, A., N. Mizuno, M. Takai, E. Otaka and S. Osawa: Molecular and metabolic properties of messenger RNA from normal and T2-infected E. coli. J. molec. Biol. 5, 251–264 (1962).

    Google Scholar 

  • Keyl, H.-G.: Die cytologische Diagnostik der Chironomiden. III. Diagnose von Chironomus parathummi n. sp. mit Ergänzungen zur Bestimmungstabelle. Arch. Hydrobiol. 58, 1–6 (1961).

    Google Scholar 

  • —, u. I. Keyl: Die cytologische Diagnostik der Chironomiden I. Bestimmungstabelle für die Gattung Chironomus auf Grund der Speicheldrüsenchromosomen. Arch. Hydrobiol. 56, 43–57 (1959).

    Google Scholar 

  • —, u. C. Pelling: Differentielle DNS-Replikation in den Speicheldrüsen-Chromosomen von Chironomus Thummi. Chromosoma (Berl.) 14, 347–359 (1963).

    Google Scholar 

  • —, u. K. Strenzke: Taxonomie und Cytologie von zwei Subspezies der Art Chironomus Thummi. Z. Naturforsch. 11b, 727–735 (1956).

    Google Scholar 

  • MacGregor, H. C., and H. G. Callan: The actions of enzymes on lampbrush chromosomes. Quart. J. micr. Sci. 103 (2), 173–203 (1962).

    Google Scholar 

  • McMaster-Kaye, R.: The metabolic characteristics of nucleolar, chromosomal, and cytoplasmic ribonueleic acid of Drosophila salivary glands. J. biophys. biochem. Cytol. 8, 365–378 (1960); - Symposium: Synthetic processes in the cell nucleus. III. The metabolism of nuclear ribonueleic acid in salivary glands of Drosophila repleta. J. Histochem. Cytochem. 10, 154–161 (1962).

    Google Scholar 

  • —, and J. H. Taylor: Evidence for two metabolically distinct types of ribonueleic acid in chromatin and nucleoli. J. biophys. biochem. Cytol. 4, 5–11 (1958).

    Google Scholar 

  • Mechelke, F.: Reversible Strukturmodifikationen der Speicheldrüsenchromosomen von Acricotopus lucidus. Chromosoma (Berl.) 5, 511–543 (1953); - Beziehungen zwischen der Menge der DNS und dem Ausmaß der potentiellen Oberflächenentfaltung von Riesenchromosomenloci. Naturwissenschaften 46, 609 (1959).

    Google Scholar 

  • Monier, R., S. Naono, D. Hayes, F. Hayes and F. Gros: Studies on the heterogeneity of messenger RNA from E. coli. J. molec. Biol. 5, 311–324 (1962).

    Google Scholar 

  • Nirenberg, M. W., and J. H. Matthaei: The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides. Proc. nat. Acad. Sci. (Wash.) 47, 1588–1602 (1961).

    Google Scholar 

  • Oehlert, W.: Autoradiographische Untersuchungen zur RibonukleinsäureSynthese in den verschiedenen Strukturen der Zelle. Beitr. path. Anat. 124, 311–350 (1961).

    Google Scholar 

  • Otaka, E., S. Osawa, Y. Oota, A. Ishihama and H. Mitsui: Synthesis of ribonueleic acids in microbial cells. I. Ribosomal-ribonucleic acid synthesis in growing bacterial cells. Biochim. biophys. Acta (Amst.) 55, 310–325 (1962).

    Google Scholar 

  • Pavan, C.: Morphological and physiological aspects of chromosomal activities. X. Intern. Congr. of Genetics 1958, pp. 321–336.

  • Pelling, C.: Chromosomal synthesis of ribonucleic acid as shown by incorporation of uridine labeled with tritium. Nature (Lond.) 184, 655–656 (1959); - Application of tritiated compounds to the midge Chironomus and some aspects of the metabolism of salivary gland chromosomes. Symp. Detect. Use Tritium. IAEA, Wien 1962, pp. 327–334.

    Google Scholar 

  • Perry, R. P.: On the nucleolar and nuclear dependence of cytoplasmic RNA synthesis in HeLa cells. Exp. Cell Res. 20, 216–220 (1960); - The cellular sites of synthesis of ribosomal and 4s RNA. Proc. nat. Acad. Sci. (Wash.) 48, 2179–2186 (1962).

    Google Scholar 

  • — in collaboration with M. Errera, A. Hell and H. Dürwald: Kinetics of nucleoside incorporation into nuclear and cytoplasmic RNA. J. biophys. biochem. Cytol. 11, 1–13 (1961).

    Google Scholar 

  • Poulson, D. F., and C. W. Metz: Studies on the structure of nucleolus forming regions and related structures in the giant salivary gland chromosomes of Diptera. J. Morph. 63, 363–395 (1938).

    Google Scholar 

  • Prescott, D. M.: The nuclear dependence of RNA synthesis in Acanthamoeba sp. Exp. Cell Res. 19, 29–34 (1960).

    Google Scholar 

  • —, and R. F. Kimball: Relation between RNA, DNA and protein synthesis in the replicating nucleus of Euplotes. Proc. nat. Acad. Sci. (Wash.) 47, 686–693 (1961).

    Google Scholar 

  • Rho, J. A., and J. Bonner: The site of ribonucleic acid synthesis in the isolated nucleus. Proc. nat. Acad. Sci. (Wash.) 47, 1611–1619 (1961).

    Google Scholar 

  • Risebrough, R. W., A. Tissières and J. D. Watson: Messenger-RNA attachment to active ribosomes. Proc. nat. Acad. Sci. (Wash.) 48, 430–436 (1962).

    Google Scholar 

  • Rudkin, G. T.: The ultraviolet absorption of puffed and unpuffed homologous regions in the salivary gland chromosomes of Drosophila melanogaster. Genetics 40, 593 (1955).

    Google Scholar 

  • —, and S. L. Corlette: Disproportionate synthesis of DNA in a polytene chromosome region. Proc. nat. Acad. Sci. (Wash.) 43, 964–968 (1957).

    Google Scholar 

  • —, and P. S. Woods: Incorporation of H3-cytidine and H3-thymidine into giant chromosomes of Drosophila during puff formation. Proc. nat. Acad. Sci. (Wash.) 45, 997–1003 (1959).

    Google Scholar 

  • Sagik, B. P., M. H. Green, M. Hayashi and S. Spiegelman: Size distribution of “informational” RNA. Biophys. J. 2, 409–421 (1962).

    Google Scholar 

  • Scholtissek, C.: Verwandtschaftsbeziehungen zwischen den Ribonukleinsäuren des Zellkerns, der Mitochondrien, Mikrosomen und des Zellsaftes bei Rattenleber, Milz und Nieren. Biochem. Z. 332, 458–466 (1960).

    Google Scholar 

  • Simon, H., H. Daniel u. J. F. Klebe: Die Messung von 14C und 3H in der Gasphase. Angew. Chem. 71, 303–308 (1959).

    Google Scholar 

  • Sirlin, J. L.: Cell sites of RNA and protein synthesis in the salivary gland of Smittia (Chironomidae). Exp. Cell Res. 19, 177–180 (1960).

    Google Scholar 

  • —, and G. R. Knight: The pattern of protein sulphur after Feulgen hydrolysis in the salivary gland chromosomes of Drosophila melanogaster. Chromosoma (Berl.) 9, 119–159 (1958).

    Google Scholar 

  • Swift, H.: Nucleic acids and cell morphology in dipteran salivary glands. In: The molecular control of cellular activity, pp. 73–125. McGraw-Hill: New York 1962.

    Google Scholar 

  • Volkin, E., and L. Astrachan: Intercellular distribution of labeled ribonucleic acid after phage infection of E. coli. Virology 2, 433–437 (1956).

    Google Scholar 

  • Woods, P. S.: RNA in nuclear-cytoplasmic interaction. Brookhaven Symp. in Biol. 12, 153–174 (1959) ; Autoradiographic studies of ribonucleic acid metabolism with tritium-labelled cytidine. Symp. Detect. Use Tritium. IAEA, Wien 1962, pp. 335–346.

    Google Scholar 

  • —, and J. H. Taylor: Studies of ribonucleio acid metabolism with tritiumlabelled cytidine. Lab. Invest. 8, 309–318 (1959).

    Google Scholar 

  • Yankofsky, S. A., and S. Spiegelman: The identification of the ribosomal RNA cistron by sequence complementarity. I. Specifity of complex formation. Proc. nat. Acad. Sci. (Wash.) 48, 1069–1078 (1962a); - The identification of the ribosomal RNA cistron by sequence complementarity. II. Saturation of and competitive interaction at the RNA cistron. Proc. nat. Acad. Sci. (Wash.) 48, 1466–1472 (1962b).

    Google Scholar 

  • Zalokar, M.: Nuclear origin of ribonucleic acid. Nature (Lond.) 183, 1330 (1959) ; - Sites of ribonucleic acid and protein synthesis in Drosophila. Exp. Cell Res. 19, 184–186 (1960).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Mit Unterstützung der Deutschen Forschungsgemeinschaft und des Bundesministeriums für wissenschaftliche Forschung (Förderungsvorhaben St.N. 141)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pelling, C. Ribonukleinsäure-Synthese der Riesenchromosomen. Chromosoma 15, 71–122 (1964). https://doi.org/10.1007/BF00326915

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00326915

Navigation