Summary
An analysis of the ultrastructure of neuropeptide Y-immunoreactive neurons in rat striatum revealed the presence of a cilium in half of the neurons serially sectioned in part, and in a quarter of the neurons observed in single sections. It is speculated that the cilium is a developmental remnant, i.e., a sign of the less differentiated state of the NPY-containing neurons compared with the other neurons, and that this could explain the plasticity of this type of neuron after lesions.
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References
Allen RA (1965) Isolated cilia in inner retinal neurons and in retinal pigment epithelium. J Ultrastruct Res 12:730–747
Chung JW, Keefer DA (1976) Occurrence of cilia in the fundus striati of the cat. Cell Tissue Res 175:421–424
Dahl HA (1963) Fine structure of cilia in rat cerebral cortex. Z Zellforsch 60:369–386
De Robertis E (1956) Electron microscope observations on the submicroscopic organization of the retinal rods. J Biophys Biochem Cytol 2:319–330
Goodman LS, Gilman A (1975) The pharmacological basis of therapeutics. McMillan, New York
Hsu SM, Raine L, Fanger H (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29:577–580
Karlsson U (1966) Three-dimensional studies of neurons in the lateral geniculate nucleus of the rat. I. Organelle organization in the perikaryon and its proximal branches. J Ultrastruct Res 16:429–481
Kemali M, Gioffre D (1978) Non-ependymal cilia in the habenulae and the interpeduncular nucleus of the frog tadpole. Cell Tissue Res 195:527–535
Kerkerian L, Bosler O, Pelletier G, Nieoullon A (1986) Striatal neuropeptide Y neurons are under the influence of the nigrostriatal depaminergic pathway: immunohistochemical evidence. Neurosci Lett 66:106–112
Kerkerian L, Salin P, Nieoullon A (1989) Cortical regulation of striatal neuropeptide Y (NPY)-containing neurons in the rat. Eur J Neurosci 2:181–189
Kowall NW, Ferrante RJ, Beal mF, Richardson EP Jr, Sofroniew MV, Cuello AC, Martin JB (1987) Neuropeptide Y, somatostatin, and reduced nicotinamide adenine dinucleotide phosphate diaphorase in the human striatum: a combined immunocytochemical and enzyme histochemical study. Neuroscience 20:817–828
Mandl L, Megele R (1989) Primary cilia in normal human neocortical neurons. Z Mikrosk Anat Forsch 103:425–430
Marrero A, Martin JM, Perez MA, Medina L, Martin A (1987) Pressence of centrioles and ciliary roots during the embryonic development in the reptilian cerebellum. Z Mikrosk Anat Forsch 101:1023–1026
Milhaud M, Pappas GD (1968) Cilia formation in the adult cat brain after pargyline treatment. J Cell Biol 37:599–609
Palay S (1961) Structural peculiarities of the neurosecretory cells in the preoptic nucleus of the goldfish, Carassius auratus. Anat Rev 139:262
Rafols JA, Fox CA (1971/72) Further observations on the spiny neurons and synaptic endings in the striatum of the monkey (Saimiri sciureus). J Hirnforsch 13:299–308
Ruela C, Tavares MA, Paula-Barbarosa MM (1981) Cilia in stellate nejrons of the rat cerebellum. Experientia 37:197–198
Schwartzberg M, Unger J, Weindl A, Lange W (1990) Distribution of neuropeptide Y in the prosencephalon of man and cotton head tamarin (Saguirus oedipus): colocalisation with somatostatin in neurons of striatum and amygdala. Anat Embryol 181:157–166
Smith Y, Parent A (1986) Neuropeptide Y-immunoreactive neurons in the striatum of the cat and monkey: morphological characteristics, intrinsic organization and colocalization with somatostatin. Brain Res 372:241–252
Vigh-Teichmann I, Vigh B, Aros B (1976a) Cerebrospinal fluid-contacting neurons, ciliated perikarya and “peptidergic” synapses in the magnocellular preoptic nucleus of the teleostean fishes. Cell Tissue Res 165:397–413
Vigh-Teichmann I, Vigh B, Aros B (1976b) Ciliated neurons and different types of synapses in the anterior hypothalamic nuclei of reptiles. Cell Tissue Res 174:139–160
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This work is part of the thesis of G. Wolfrum submitted to the Ludwig-Maximilians-Universität in partial fulfillment for the requirements of a Dr. rer. nat. degree
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Wolfrum, G., Nitsch, C. High frequency of ciliated neuropeptide Y-immunoreactive neurons in rat striatum. Cell Tissue Res 267, 199–202 (1992). https://doi.org/10.1007/BF00318705
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DOI: https://doi.org/10.1007/BF00318705