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Studies on siderophore production and effect of iron deprivation on the outer membrane proteins of Madurella mycetomatis

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Abstract

The purpose of this investigation was to determine whether Madurella mycetomatis, the most frequent agent of eumycotic mycetomas, produces siderophores and synthesizes new outer membrane proteins under iron-starvation conditions. Siderophore production, only of the hydroxamate type, was demonstrated in all nine strains tested. It was regulated by extracellular iron concentrations. Under iron-restricted conditions, M. mycetomatis expressed various outer membrane iron-regulated proteins, particularly of 24-kilodalton, that may participate in iron metabolism.

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Mezence, M.I.B., Boiron, P. Studies on siderophore production and effect of iron deprivation on the outer membrane proteins of Madurella mycetomatis . Current Microbiology 31, 220–223 (1995). https://doi.org/10.1007/BF00298377

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