Skip to main content
SpringerLink
Log in

Polymorphismus der erythrocytären NADH-Diaphorase in der westdeutschen Bevölkerung

Polymorphism of red cell NADH-diaphorase in western German population

  • Originalarbeiten
  • Published:
Humangenetik Aims and scope Submit manuscript

Summary

Phenotypes of the red cell NADH-diaphorase were established amongst 1008 non related Germans from the Cologne area (564 females and 444 males). The following NADH-diaphorase types were identified: 991xDia 1-1, 4xDia 2-1, 1xDia 2-2, 5xDia 4-1 and 7xDia 5-1. Concerning the western German population the following gene frequencies were calculated: Dia1=0.9913, Dia2=0.0025, Dia4=0.0025 and Dia5=0.0035.

Zusammenfassung

Bei 1008 unausgewählten nicht verwandten Deutschen aus dem Kölner Raum (564 Frauen und 444 Männer) wurden die Phänotypen der erythrocytären NADH-Diaphorase bestimmt. 991mal wurde der Typ Dia 1-1 nachgewiesen, 4mal Dia 2-1, 1mal Dia 2-2, 5mal Dia 4-1 und 7mal Dia 5-1. Für die westdeutsche Bevölkerung wurden folgende Genfrequenzen geschätzt: Dia 1=0,9913, Dia 2=0,0025, Dia 4=0,0025 und Dia 5=0,0035.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  • Brewer, G. J., Eaton, J. W., Knutsen, C. S., Beck, C. C.: A starch-gel electrophoretic method for the study of diaphorase isozymes and preliminary results with sheep and human erythrocytes. Biochem. biophys. Res. Commun. 29, 198–204 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Detter, J. C., Anderson, J. E., Giblett, E. R.: NADH diaphorase: an inherited variant associated with normal methemoglobin reduction. Amer. J. hum. Genet. 22, 100–104 (1970).

    CAS  PubMed  PubMed Central  Google Scholar 

  • Hopkinson, D. A., Corney, G., Cook, P. J. L., Robson, E. B., Harris, H.: Genetically determined electrophoretic variants of human red cell NADH diaphorase. Ann. hum. Genet. 34, 1–10 (1970).

    Article  CAS  PubMed  Google Scholar 

  • Kaplan, J.-C., Beutler, E.: Electrophoresis of red cell NADH- and NADPH-diaphorases in normal subjects and patients with congenital methemoglobinemia. Biochem. biophys. Res. Commun. 29, 605–610 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Tariverdian, G., Ritter, H., Wendt, G. G.: Genetisch kontrollierte Varianten der NADH-Diaphorase. Humangenetik 11, 75–77 (1970).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Hygiene-Institut der Universität Köln, Köln, Deutschland

    B. G. Potrafki, H. Hellenbroich & G. Pulverer

Authors
  1. B. G. Potrafki
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Hellenbroich
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. Pulverer
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Potrafki, B.G., Hellenbroich, H. & Pulverer, G. Polymorphismus der erythrocytären NADH-Diaphorase in der westdeutschen Bevölkerung. Hum Genet 15, 182–185 (1972). https://doi.org/10.1007/BF00295746

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00295746

Search

Navigation