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Correlation between 1.25 dihydroxyvitamin D serum levels and fractional rate of intestinal calcium absorption in hypercalciuric nephrolithiasis. role of phosphate

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Summary

Different mechanisms could explain the elevated calcium elimination, the main cause of calcium oxalate renal stones. Our results suggest that phosphate levels are decreased in patients with absorptive hypercalciuric nephrolithiasis and elevated serum dihydroxyvitamin D. This could be the reason why in this group of patients oral phosphate treatment prevented hypercalciuria and renal lithiasis.

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References

  1. Reicher H, Koefer P, Norman AW (1989) The role of the vitamin D endocrine system in health and disease. N Engl Med 320:980–991

    Google Scholar 

  2. Pak CYC, Ohata M, Lawrence EC et al. (1974) The hypercalciurias. J Clin Invest 54:387–399

    Google Scholar 

  3. Marshal DH, Nordin BEL (1969) Kinetic analysis of plasma radioactivity after oral ingestion of radiocalcium. Nature 222:797

    Google Scholar 

  4. Kaplan RA, Haussler MR, Deftos L et al. (1977) The role of 1α.25-dihydroxyvitamin D in the mediation of intestinal hyperparathyroidism and absorptive hypercalciuria. J Clin Invest 59:756–760

    Google Scholar 

  5. Roberts DH and Knox FG (1990) Renal phosphate handling and calcium nephrolithiasis: role of dietary phosphate and phosphate leak. Seminars in Nephrology 10:24–30

    Google Scholar 

  6. Tieder M, Modai D, Shakad U et al. (1987) Hereditary hypophosphatemic rickets with hypercalciuria. N Engl J Med 316:611–617

    Google Scholar 

  7. Cheng L, Dersch C, Kraus E et al. (1984) Renal adaptation to phosphate load in the acutely thyroparathyroidectomized rat: Rapid alteration in brush border membrane phosphate transport. Am J Physiol 246:F488-F494

    Google Scholar 

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Authors and Affiliations

  1. Laboratorio de la Unidad Metabólica, Fundación Jiménez Diaz, 28040, Madrid, Spain

    M. V. Alvarez-Arroyo, M. L. Traba, A. Rapado, C. de la Piedra & M. Torralbo

Authors
  1. M. V. Alvarez-Arroyo
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  2. M. L. Traba
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  3. A. Rapado
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  4. C. de la Piedra
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  5. M. Torralbo
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This work was supported by FlSss 89/0799

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Alvarez-Arroyo, M.V., Traba, M.L., Rapado, A. et al. Correlation between 1.25 dihydroxyvitamin D serum levels and fractional rate of intestinal calcium absorption in hypercalciuric nephrolithiasis. role of phosphate. Urol. Res. 20, 96–97 (1992). https://doi.org/10.1007/BF00294348

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  • DOI: https://doi.org/10.1007/BF00294348

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