Summary
A paracentric inversion of chromosome 2 is described for the first time. The breakpoints were localized in the bands q31 and q36. The paracentric inversion was initially identified in a female with repeated abortions and thereafter detected in eight other family members over three generations. The meiotic consequences and the risk for liveborn unbalanced chromosomal recombinants is discussed.
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Schmid, M., Hofmann, R., Köhler, J. et al. Familial paracentric inversion in(2)(q31q36). Hum Genet 71, 270–272 (1985). https://doi.org/10.1007/BF00284590
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DOI: https://doi.org/10.1007/BF00284590