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Cytological and cytogenetical studies on brain tumors

II. Hyperdiploidy, a rare event in human primary meningiomas

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Summary

Among 70 human meningiomas cytogenetically investigated by us up till now, only 4 tumors showed a hyperdiploidy. 2 of them had a uniform stemline with 47 chromosomes (47,XX,G+ and 47, XY, C(?E)+); the other 2 meningiomas had a stemline with a modal number of 53 (55) chromosomes.

Zusammenfassung

Unter 70 menschlichen Meningiomen, die von uns bis jetzt untersucht worden sind, fanden sich lediglich 4 mit einem hyperdiploiden Chromosomensatz. 2 hatten eine einheitliche Stammlinie mit 47 Chromosomen (47, XX, G+ bzw. 47, XY, C(?E)+); die übrigen beiden Meningiome hatten Stammlinien mit einer sehr einheitlichen Modalzahl von 53 (55) Chromosomen.

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Zankl, H., Singer, H. & Zang, K.D. Cytological and cytogenetical studies on brain tumors. Hum Genet 11, 253–257 (1971). https://doi.org/10.1007/BF00274746

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