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Distribution of mitochondrially inherited drug-resistance genes to tetrads from young zygotes in yeast

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Summary

Pairs of strains of opposite mating type were isolated from a strain of Saccharomyces cerevisiae. From these isogenic strains, mitochondrially inherited resistant mutants to antimycin A and erythromycin were isolated. By using the two resistance genes as mitochondrial markers, it was proposed that the distribution of the mitochondrial genomes from zygotes to tetrads seemed not to be random but the genomes from either a or α parent would be selected with approximately equal frequencies after zygote formation and subsequently distributed uniparentally to meiotic products.

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Authors and Affiliations

  1. Biology Division, College of General Education, Kobe University, 657, Kobe, Japan

    Akira Uchida

  2. Biological Laboratory, Nara University of Education, 630, Nara, Japan

    Kohta Suda

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  1. Akira Uchida
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  2. Kohta Suda
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Communicated by F. Kaudewitz

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Uchida, A., Suda, K. Distribution of mitochondrially inherited drug-resistance genes to tetrads from young zygotes in yeast. Molec. Gen. Genet. 165, 191–197 (1978). https://doi.org/10.1007/BF00269906

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  • DOI: https://doi.org/10.1007/BF00269906

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