Summary
In P. putida the first four enzymes involved in the dissimilation of histidine are induced by the first intermediate of the pathway, urocanic acid. The genes specifying these enzymes, hutH, hutU, hutF and (probably) hutI appear to be clustered on the chromosome between pcaE and pcaA (genes involved in p-hydroxybenzoic acid catabolism). Two mutants which produce the histidine-dissimilitory enzymes constitutively have been isolated. They appear to carry mutations in a regulatory locus, which maps in the same region as the structural genes of the pathway.
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Communicated by P. Starlinger
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Leidigh, B.J., Wheelis, M.L. Genetic control of the histidine dissimilatory pathway in Pseudomonas putida . Molec. Gen. Genet. 120, 201–210 (1973). https://doi.org/10.1007/BF00267152
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DOI: https://doi.org/10.1007/BF00267152