Abstract
In six normal dogs the adrenals could be visualized as separate areas of radioactivity at 7–10 days after injection of 20–40 μCi 131I-iodocholesterol per kg of body weight. Image analysis revealed uptake values of 0.15–0.3% of the injected dose. In five dogs with pituitary-dependent hyperadrenocorticism the adrenals became visible at 3–5 days after injection of the radiopharmaceutical, with uptake values of 0.38–2.2%.
In six dogs with hyperadrenocorticism due to adrenocortical tumor the scintigraphy contributed to the diagnosis and the presurgical localization. The uptake values were within the normal range; the tumor could be observed at 3–10 days after injection.
Additional findings on adrenal asymmetry and a case of fluctuating pituitary-dependent hyperadrenocorticism are discussed.
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van den Brom, W.E., Rijnberk, A., Lubberink, A.A.M.E. et al. Uptake of 131I-19-cholesterol by normal and spontaneously hyperfunctioning canine adrenals. Eur J Nucl Med 4, 61–67 (1979). https://doi.org/10.1007/BF00257572
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DOI: https://doi.org/10.1007/BF00257572