Abstract
A computer based simulation program was developed to assess the usefulness of various attenuation correction algorithms and data acquisition methods in single photon emission computed tomography (SPECT) in a unified approach. The program analytically calculated projection ray sums from a mathematical model with various distributions of activities and either uniform or non uniform attenuation coefficients by using the line integrals including the effect of attenuation. Data acquisition starting at arbitrary angles, various acquisition angles, including a 180° scan and a non circular orbit of a gamma camera, including an elliptical orbit can readily be taken into consideration in our simulation program. To simulate non circular orbit data acquisition, the resolution dependence on the object distance from the collimator surface was incorporated into the simulation. This computer based simulation program allows various combinations of attenuation correction algorithms such as hybrid methods, and data acquisition methods can be evaluated under a large number of study conditions. The usefulness of this computer based simulation program is shown with several representative examples.
Similar content being viewed by others
References
Budinger TF, Gullberg GT (1974) Three-dimensional reconstruction in nuclear medicine emission imaging. IEEE Trans Nucl Sci 21:2–20
Burow RD, Pond M, Schafer AW, Becker L (1979) “Circumferential profiles:” A new method for computer analysis of thallium-201 myocardial perfusion images. J Nucl Med 20:771–777
Chang LT (1978) A method for attenuation correction in radionuclide computed tomography. IEEE Trans Nucl Sci 25:638–643
Coleman RE, Jaszczak RJ, Cobb FR (1982) Comparison of 180° and 360° data collection in thallium-201 imaging using SPECT. J Nucl Med 23:655–660
Eisner RL, Nowak DJ, Pettigrew R, Fajman W (1986) Fundamentals of 180° acquisition and reconstruction in SPECT imaging. J Nucl Med 27:1717–1728
Hoffman EJ (1982) 180° compared with 360° sampling in SPECT. J Nucl Med 23:745–747
Gilland DR, Tsui BMW, McCartney WH, Perry JR (1988) Determination of the optimum filter function for SPECT imaging. J Nucl Med 29:643–650
Gottschalk SC, Salem D, Lim CB, Wake RH (1983) SPECT resolution and uniformity improvements by noncircular orbit. J Nucl Med 24:822–828
Jaszczak RJ, Greer KL, Coleman RE (1988) SPECT using a specially designed cone beam collimator. J Nucl Med 29:1398–1405
Murase K, Itoh H, Mogami H, Ishine M, Kawamura M, Iio A, Hamamoto K (1987) A comparative study of attenuation correction algorithms in single photon emission computed tomography (SPECT). Eur J Nucl Med 13:55–62
Shepp LA, Logan BF (1974) Reconstruction interior head tissue from X-ray transmissions. IEEE Trans Nucl Sci 21:228–236
Sorenson JA (1974) Quantitative measurement of radioactivity in vivo by whole-body counting. Instrument Nucl Med 2:311–348
Tamaki N, Mukai T, Ishii Y, Fujita T, Minato K, Yonekura Y, Tamaki S, Kambara H, Kawai C, Torizuka K (1982) Comparative study of thallium emission myocardial tomography with 180° and 360° data collection. J Nucl Med 23:661–666
Tamaki N, Mukai T, Ishii Y, Yonekura Y, Yamamoto K, Kadota K, Kambara H, Kawai C, Torizuka K (1983) Multiaxial tomography of heart chamber by gated blood-pool emission computed tomography using a rotating gamma canera. Radiology 147:547–554
Tanaka E, Toyama H, Murayama H (1984) Convolutional image reconstruction for quantitative single photon emission computed tomography. Phys Med Biol 29:1489–1500
Tsui BMW, Gullberg GT, Edgerton ER, Gilland DR, Perry JR, McCartney WH (1986) Design and clinical utility of a fan beam collimator for SPECT imaging of the head. J Nucl Med 27:810–819
Walters TE, Simon W, Chesler DA, Correia JA (1981) Attenuation correction in gamma emission computed tomography. J Comput Assist Tomogr 5:89–94
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Murase, K., Tanada, S., Higashino, H. et al. A unified computer program for assessment of attenuation correction and data acquisition methods in single photon emission computed tomography (SPECT). Eur J Nucl Med 15, 248–253 (1989). https://doi.org/10.1007/BF00257542
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00257542