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A deactivation model for immobilized and soluble enzymes

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Summary

A first-order deactivation model which includes a step that does not destroy enzyme activity, but is a compulsory precursor of the step that does, is shown to fit reasonably well the immobilized and soluble enzyme deactivation data presented. The deactivation rate coefficient increases with time, and the model may be generalized to include n such compulsory precursors.

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Authors and Affiliations

  1. Chemical Engineering Division, National Chemical Laboratory, USA

    Ajit Sadana

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  1. Ajit Sadana
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Sadana, A. A deactivation model for immobilized and soluble enzymes. Biotechnol Lett 2, 279–284 (1980). https://doi.org/10.1007/BF00239857

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  • DOI: https://doi.org/10.1007/BF00239857

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