Summary
The incidence of deformed optic nerves (DON) in C57BL/6J-C2J mice is similar to that of a pigmented substrain of Long-Evans rats and much less than that of an albino substrain of Sprague Dawley rats. C57BL/6J-c2J albinos have no more DON than do coisogenic black mice. This suggests that albinism is not a factor in DON and that observed DON in Sprague Dawley rats are strain or substrain characteristics.
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References
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Westenberg, I.S. Deformed optic nerves in coisogenic albino and pigmented C57BL/6J-c2J mice. Exp Brain Res 37, 615–617 (1979). https://doi.org/10.1007/BF00236829
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DOI: https://doi.org/10.1007/BF00236829