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The role of the claustrum in the bilateral control of frontal oculomotor neurons in the cat

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Summary

The effect of claustrum (CL) stimulation on the spontaneous unitary activity of ipsi and contralateral frontal oculomotor neurons, was studied in chloralose-anaesthetized cats. A total of 205 units was bilaterally recorded in the medial oculomotor area, homologous of the primate “frontal eye fields” 127 neurons were identified as projecting to the superior colliculus; for 33 of these last units stimulation of the ipsilateral CL provoked an excitatory effect lasting 10–25 ms and appearing with a latency of 5–15 ms; on 8 units the excitatory effect was followed by an inhibition lasting 100–250 ms. Ninety-eight of the 127 neurons were also tested through activation of the contralateral CL: 13 cells showed an excitatory effect lasting 10–35 ms and appearing with a latency of 20–50 ms. In three of the thirteen units the excitatory effect was followed by an inhibition lasting 100–150 ms. Complete section of the corpus callosum abolished the contralateral CL effect, suggesting the existence of a direct claustro-contralateral oculomotor cortex pathway running through the corpus callosum. The results could support the hypothesis that the CL may play a role in the bilateral control of the visuomotor performance.

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References

  • Andersen DL (1968) Some striatal connections to the claustrum. Exp Neurol 20:261–267

    Google Scholar 

  • Barbas H, Mesulam MM (1981) Organization of afferent input to subdivisions of area 8 in the rhesus monkey. J Comp Neurol 200:407–431

    Google Scholar 

  • Bonvallet M, Dell P, Hugelin A (1952) Projections olfactives, gustatives, viscerales, vagales, visuelles et auditives au niveau des formations grises du cerveau antérieur du chat. J Physiol (Paris) 44:222–224

    Google Scholar 

  • Boyapati J, Henry GH (1985) The character and influence of the claustral pathway to the striate cortex of the cat. Exp Brain Res 61:141–152

    Google Scholar 

  • Carey RG, Bear MF, Diamond IT (1980) The laminar organization of the reciprocal projection between the claustrum and striate cortex in the tree shrew Tupaia glis. Brain Res 184:193–198

    Google Scholar 

  • Carey RG, Neal TL (1986) Reciprocal connections between claustrum and visual thalamus in the tree shrew (Tupaia glis). Brain Res 386:155–168

    Google Scholar 

  • Carman JB, Cowan WM, Powell TPS (1964) The cortical projection upon the claustrum. J Neurosurg Psychiat 27:46–51

    Google Scholar 

  • Cortimiglia R, Crescimanno G, Salerno MT, Amato G, Infantellina F (1987) Electrophysiological relationship between claustrum and contralateral area 4 and 6 pyramidal tract neurons. Neurosci Lett 74:193–198

    Google Scholar 

  • Crescimanno G, Salerno MT, Cortimiglia R, Amato G, Infantellina F (1984) Functional relationship between claustrum and pyramidal tract neurons, in the cat. Neurosci Lett 44:125–129

    Google Scholar 

  • Crescimanno G, Salerno MT, Cortimiglia R, Amato G (1989) Claustral influence on ipsi- and contralateral motor cortical areas in the cat. Brain Res Bull 22:839–843

    Google Scholar 

  • Druga R (1966) The claustrum of the cat (Felix domestica). Folia Morphol (Praha) 14:7–16

    Google Scholar 

  • Druga R (1972) Efferent projections from the claustrum: an experimental study using Nauta's method. Folia Morphol (Praha) 20:163–165

    Google Scholar 

  • Druga R (1982) Claustro-neocortical connections in the cat and rat demonstrated by HRP tracing technique. J Hirnforsch 23:191–202

    Google Scholar 

  • Guitton D, Mandl G (1978) Frontal “oculomotor” area in alert cat. I. Eye movements and neck activity evoked by stimulation. Brain Res 149:295–312

    Google Scholar 

  • Guitton D, Mandl G. (1978) Frontal “oculomotor” area in alert cat. II. Unit discharge associated with eye movements and neck muscle activity. Brain Res 149:313–327

    Google Scholar 

  • Hartwich-Young R, Weber JT (1986) The projection of frontal oculomotor areas to the superior colliculus in the domestic cat. J Comp Neurol 253:342–357

    Google Scholar 

  • Hinova-Palova DV, Paloff AM, Usunoff KG, Dimova RN, Yossifov TY, Ivanov DP (1988) Reciprocal connections between the claustrum and the auditory cortical fields in the cat: an experimental study using light- and electron microscopic anterograde degeneration methods, and the horseradish peroxidase retrograde axonal tranport. J Hirnforsch 3:255–278

    Google Scholar 

  • Irvine DRF, Brugge JF (1980) Afferent and efferent connections between the claustrum and parietal association cortex in cat: a horseradish peroxidase an autoradiographic study. Neurosci Lett 20:5–10

    Google Scholar 

  • Jayaraman A, Updyke BV (1979) Organization of visual cortical projections to the claustrum in the cat. Brain Res 178:107–115

    Google Scholar 

  • Kaufman EPS, Rosenquist AC (1985) Efferent projections of the thalamic nuclei in the cat. Brain Res 335:257–279

    Google Scholar 

  • Kemp JM, Powell TPS (1970) The cortico-striate projection in the monkey. Brain 93:525–546

    Google Scholar 

  • Kunzle H, Akert K (1977) Efferent connections of cortical area 8 (frontal eye field) in Macaca fascicularis: a reinvestigation using the autoradiographic technique. J Comp Neurol 173:147–164

    Google Scholar 

  • LeVay S, Sherk H (1981) The visual claustrum of the cat. I. Structure and connections. J Neurosci 1:956–980

    Google Scholar 

  • LeVay S (1986) Sinaptic organization of claustral and geniculate afferents to the visual cortex of the cat. J Neurosci 6:3564–3575

    Google Scholar 

  • Li ZK, Takada M, Hattori T (1986) Topographic organization and collateralization of claustrocortical projections in the rat. Brain Res Bull 17:529–532

    Google Scholar 

  • Macchi G, Bentivoglio M, Minciacchi D, Molinari M (1981) The organization of the claustro-cortical projections in the cat studied by means of the HRP retrograde axonal transport. J Comp Neurol 195:681–695

    Google Scholar 

  • Macchi G, Bentivoglio M, Minciacchi D, Molinari M (1983) Claustroneocortical projections studied in the cat by means of multiple retrograde fluorescent tracing. J Comp Neurol 215:121–134

    Google Scholar 

  • Mamos L, Narkiewicz O, Morys J (1986) Neurons of the claustrum in the cat: a Golgi study. Acta Neurobiol Exp 46:171–178

    Google Scholar 

  • Markowitsch HJ, Pritzel M, Divac I (1979) Cortical afferences to the prefrontal cortex of the cat: a study with the horseradish peroxidase technique. Neurosci Lett 11:115–120

    Google Scholar 

  • Markowitsch HJ, Irle E, Bang-Olson R, Flindt-Egebak P (1984) Claustral efferents to the cat's limbic cortex studied with retrograde and anterograde tracing techniques. Neuroscience 12:409–425

    Google Scholar 

  • Minciacchi D, Molinari M, Bentivoglio M, Macchi G (1985) The organization of ipsi- and contralateral claustrocortical system in rat with notes on the bilateral claustrocortical projections in cat. Neuroscience 16:557–576

    Google Scholar 

  • Mori A, Waters RS, Asanuma H (1983) Low threshold motor effect produced by stimulation of area preinsularis (2pr I) of the secondary sensory cortex in the cat: input-output relationships. Exp Brain Res 51:108–116

    Google Scholar 

  • Narkiewicz O (1964) Degenerations in the claustrum after regional neocortical ablations in the cat. J Comp Neurol 123:335–356

    Google Scholar 

  • Neal JW, Pearson RCA, Powell TPS (1986) The relationship between the auditory cortex and the claustrum in the cat. Brain Res 366:145–151

    Google Scholar 

  • Norita M (1977) Demonstration of bilateral claustrocortical connections in the cat with the method of retrograde axonal transport of horseradish peroxidase. Arch Histol Jpn 40:1–10

    Google Scholar 

  • Pearson RCA, Brodal P, Gatter KC, Powell TPS (1982) The organization of the connections between the cortex and the claustrum in the monkey. Brain Res 234:435–441

    Google Scholar 

  • Ptito M, Lassonde MC (1981) Effects of claustral stimulation on the properties of visual cortex neurons in the cat. Exp Neurol 73:315–320

    Google Scholar 

  • Riche D, Lanoir J (1978) Some claustro-cortical connections in the cat and baboon as studied by retrograde horseradish peroxidase transport. J Comp Neurol 177:435–444

    Google Scholar 

  • Salerno MT, Cortimiglia R, Crescimanno G, Amato G, Infantellina F (1984) Effects of claustrum stimulation on spontaneous bioelectrical activity of motor cortex neurons in the cat. Exp Neurol 86:227–239

    Google Scholar 

  • Salerno MT, Cortimiglia R, Crescimanno G, Amato G (1989) Effect of claustrum activation on the spontaneous unitary activity of frontal eye field neurons in the cat. Neurosci Lett 98:299–304

    Google Scholar 

  • Sanides D, Buchholtz CS (1979) Identification of the projection from the visual cortex to the claustrum by anterograde axonal transport in the cat. Exp Brain Res 34:197–200

    Google Scholar 

  • Segundo JP, Machne X (1956) Unitary responses to afferent volleys in lenticular nucleus and claustrum. J Neurophysiol 19:325–339

    Google Scholar 

  • Sherk H (1986) The claustrum and the cerebral cortex. In: Jones EJ, Peters A (eds) Cerebral cortex, Vol 5. Plenum Publishing Corporation, pp 467–499

  • Schlag J, Schlag-Rey M (1970) Induction of oculomotor responses by electrical stimulation of the prefrontal cortex in the cat. Brain Res 22:1–13

    Google Scholar 

  • Shameem N, Sanderson K, Dreher B (1984) Claustral afferents to the rat's visual cortex. Neurosci Lett 49:247–252

    Google Scholar 

  • Sloniewski P, Usunoff KG, Pilgrim CH (1985) Efferent connections of the claustrum to the posterior thalamic and pretectal region in the rat. Neurosci Lett 60:195–199

    Google Scholar 

  • Sloniewski P, Usunoff KG, Pilgrim CH (1986) Diencephalic and mesencephalic afferents' of the rat claustrum. Anat Embryol 173:401–411

    Google Scholar 

  • Snider RS, Niemer WT (1961) A sterotaxic atlas of the cat brain. University of Chicago Press, Chicago

    Google Scholar 

  • Spector I, Hassmannova Y, Albe-Fessard D (1970) A macrophysiological study of functional organization of the claustrum. Exp Neurol 29:31–51

    Google Scholar 

  • Squatrito S, Battaglini PP, Galletti C, Riva-Sanseverino E (1980) Autoradiographic evidence for projection from cortical visual areas 17, 18, 19 and the Clare-Bishop area to the ipsilateral claustrum in the cat. Neurosci Lett 19:265–269

    Google Scholar 

  • Trojanowski JQ, Jacobson S (1975) Peroxidase labelled subcortical afferents to pulvinar in rhesus monkey. Brain Res 97:144–150

    Google Scholar 

  • Tsumoto T, Suda K (1982) Effects of stimulation of the dorsocaudal claustrum on activities of striate cortex neurons in the cat. Brain Res 240:345–349

    Google Scholar 

  • Urbano A, Rapisarda C, Infantellina F (1966) Etude microphysiologique des afferences somatiques chez le chat. Arch Sci Biol 50:41–54

    Google Scholar 

  • Wilhite BL, Teyler TJ, Hendricks C (1986) Functional relations of the rodent claustral-entorhinal-hippocampal system. Brain Res 365:54–60

    Google Scholar 

  • Witter MP, Room P, Groenewegen HJ, Lohman AHM (1988) Reciprocal connections of the insular and piriform claustrum with limbic cortex: an anatomical study in the cat. Neuroscience 24:519–539

    Google Scholar 

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Authors and Affiliations

  1. Institute of Human Physiology, University of Palermo, Corso Tukory n. 129, I-90134, Palermo, Italy

    R. Cortimiglia, G. Crescimanno, M. T. Salerno & G. Amato

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  1. R. Cortimiglia
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  2. G. Crescimanno
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  3. M. T. Salerno
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  4. G. Amato
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Cortimiglia, R., Crescimanno, G., Salerno, M.T. et al. The role of the claustrum in the bilateral control of frontal oculomotor neurons in the cat. Exp Brain Res 84, 471–477 (1991). https://doi.org/10.1007/BF00230958

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  • DOI: https://doi.org/10.1007/BF00230958

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