Summary
In relation to neurophysiological investigations the arrangement and spatial distribution of ventral horn cells in the rat lumbar cord were studied. To this purpose the lumbar segments were sectioned transversally and stained with toluidine blue. Three main types of cells labelled N1, N2 and N3 were differentiated. Type N1 was selected for further evaluation. The number of cells was determined in 100 μ. cubes. The results are displayed in form of a stereotactic microatlas.
Similar content being viewed by others
References
Aitken, J. T., Bridger, J. E.: Neuron size and neuron population density in the lumbo-saoral region of the cat's spinal cord. J. Anat. (Lond.) 95, 38–53 (1961)
Balthasar, K.: Morphologie der spinalen Tibialis- und Peronaeus-Kerne bei der Katze: Topographie, Architektonik, Axon- und Dendritenverlauf der Motoneurone und Zwisohenneurone in the Segmenten L6-S2. Arch. Psychiat. Nervenkr. 188, 345–378 (1952)
Cooper, S., Sherrington, C. S.: Gowers tract and spinal border cells. Brain 63, 123–134 (1940)
Duncan, D.: A determination of the number of nerve fibers in the eighth thoracic and the largest lumbar ventral roots of the albino rat. J. comp. Neurol. 59, 47–60 (1934)
Granit, R., Kernell, D., Smith, R. S.: Delayed depolarization and the repetitive response to intracellular stimulation of mammalian motoneurons. J. Physiol. (Lond.) 168, 890–910 (1963)
Haug, H.: Über die exakte Feststellung der Anzahl Nervenzellen pro Volumeneinheit des Cortex cerebri, zugleich ein Beispiel für die Durchführung genauer Zählungen. Acta anat. (Basel) 67, 53–73 (1967)
Janzen, R.W.C., Speckmann, E.-J., Caspers, H.: Postsynaptische Potentiale lumbaler Motoneurone nach Cortexreizung bei der Ratte. Pflügers Arch. ges. Physiol. 316, R84 (1970)
Janzen, R.W.C., Speckmann, E.-J., Caspers, H.: Membrane potential changes of spinal motoneurons evoked by high frequency epicortical stimulation in rats. Proc. Intern. Union of Physiological Sciences, vol. IX, XXV. Intern. Congr., München, p. 528 (1971)
Kaizawa, J., Takahashi, I.: Motor cell columns in rat lumbar spinal cord. Tohoku J. exp. Med. 101, 25–34 (1970)
Klüver, H., Barrera, E.: A method for the combined staining of cells and fibers in the neurons system. J. Neuropath, exp. Neurol. 12, 400–403 (1953)
Rexed, B.: A cytoarchitectonic atlas of the spinal cord, J. comp. Neurol. 100, 297–379 (1954)
Romanes, G. J.: The motor pools of the spinal cord. In: J. C. Eccles and J. P. Schadé (eds.), Organization of the spinal cord. Progress in Brain Research, vol. 11, p. 93–116. Amsterdam-London-New York: Elsevier 1964
Schadé, J. P.: On the volume and surface area of spinal neurons. In: J. C. Eccles and J. P. Schadé (eds.), Organization of the spinal cord, Progress in Brain Research, vol. 11, p. 261–277. Amsterdam-London-New York: Elsevier 1964
Scheibel, M. E., Scheibel, A. B.: Spinal motoneurons, interneurons and Renshaw cells. Arch. ital. Biol. 104, 328–353 (1966)
Speckmann, E.-J., Caspers, H., Sokolov, W.: Aktivitätsveränderungen spinaler Neurone während und nach einer Asphyxie. Pflügers Arch. ges. Physiol. 319, 122–138 (1970)
Sprague, J. M.: Motor and propriospinal cells in the thoracic and lumbar cord of the Rhesus monkey. J. comp. Neurol. 95, 103–123 (1951)
Steiner, T. J., Turner, L. M.: Cytoarchitecture of the rat spinal cord. J. Physiol. (Lond.) 222, 123P-125P (1972)
Tamaki, K.: On the sectional areas and volume of the largest motor cells and their nuclei in the lumbar cord of the albino-rat according to sex. Anat. Rec. 56, 229–240 (1933)
Waibl, H.: Zur Topographie der Medulla spinalis der Albinoratte (Rattus norvegiens). Advances Anat. Embryol. Cell Biol., vol. 47, fasc. 6. Berlin-Heidelberg-New York: Springer 1973
Zeman, R., Innes, N.: Craigy's neuroanatomy of the rat. New York-London: Academic Press 1963
Author information
Authors and Affiliations
Additional information
The authors are greatly indebted to Professor Dr. Lange, Institute of Anatomy, University of Kiel, for his helpful advice and critical review of the manuscript.
Rights and permissions
About this article
Cite this article
Janzen, R.W.C., Speckmann, E.J. & Caspers, H. Distribution of large ventral horn cells in the lumbar cord of the rat. Cell Tissue Res. 151, 159–170 (1974). https://doi.org/10.1007/BF00222220
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00222220