Summary
A de novo and apparently balanced complex chromosome rearrangement (CCR) was found in monozygotic (MZ) twin infants with multiple congenital anomalies. The rearrangement involved 4 chromosomes with 6 breakpoints including 2p23, 2q13, 2q21.1, 3p23, 11q13.1, and 12q24.1. This seems to be the first report of a CCR in MZ twins. The relationship between this chromosome abnormality and MZ twinning is discussed.
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Wakita, Y., Narahara, K., Tsuji, K. et al. De novo complex chromosome rearrangement in identical twins with multiple congenital anomalies. Hum Genet 88, 596–598 (1992). https://doi.org/10.1007/BF00219353
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DOI: https://doi.org/10.1007/BF00219353