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Studies on the reticulo-endothelial system of the dogfish, Scyliorhinus canicula

Endocytic activity of fixed cells in the gills and peripheral blood leucocytes

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Summary

Clearance and subsequent localisation of a range of materials, including colloidal carbon, latex beads, sheep erythrocytes, bacteria and dextran were followed in the lesser spotted dogfish, Scyliorhinus canicula. It was found that two populations of peripheral blood leucocytes — monocytes and thrombocytes, but not granulocytes — were involved in clearance of the circulation. In the case of carbon, this material was cleared from the plasma after 12 h, and both the colloid-containing thrombocytes and monocytes disappeared from circulation by 8 weeks post injection. Upon injection of some of the materials, and particularly bacteria, a settling out of monocytes containing phagocytosed material was seen in the secondary lamellae and cavernous bodies of the gills. Large clumps of monocytes were found in the gills as early as 30 min post injection and these increased in size for up to one week, after which they gradually dispersed. The lining cells of the cavernous body, known as CB cells, were also responsible for the sequestration of carbon, latex beads and probably erythrocytes, but dextran and bacteria were not internalised. The origin, functions and phylogenetic significance of the CB cells are discussed.

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  1. Biomedical and Physiological Studies Research Group, School of Biological Sciences, University College of Swansea, Swansea, UK

    T. C. Hunt &  A. F. Rowley

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  1. T. C. Hunt
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  2. A. F. Rowley
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Hunt, T.C., Rowley, A.F. Studies on the reticulo-endothelial system of the dogfish, Scyliorhinus canicula . Cell Tissue Res. 244, 215–226 (1986). https://doi.org/10.1007/BF00218402

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  • DOI: https://doi.org/10.1007/BF00218402

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