Abstract
The cholangiographic and pancreatographic appearances of the acquired immunodeficiency syndrome (AIDS) associated cholangitis were evaluated in 26 patients. Twenty-four patients were diagnosed by retrograde cholangiography or endoscopic cholangiopancreatography (ERC or ERCP). One patient was diagnosed by T-tube cholangiography and another patient by transhepatic cholangiography. The radiographic findings ranged from intrahepatic ductal abnormalities with or without involvement of the extrahepatic biliary tree (eight patients) to irregularities and strictures involving the ampulla of Vater or the intrapancreatic portion of the common bile duct (CBD) with proximal dilatation (18 patients). Significant strictures involving the juxta-ampullary pancreatic duct were identified in six of 12 patients. Twenty-one of the 26 patients had associated infections which included: Cryptosporidium (CS), Mycobacterium avium intracellulare (MAI), cytomegalovirus (CMV), Microsporidium (MSP), and Isospora (ISP). Three patients were operated upon for acute acalculous cholecystitis. In each instance, organisms were identified in both the bile duct and the inflamed gallbladder.
Similar content being viewed by others
References
Blumberg RS, Kelsey P, Perrone T, Dickerson R, Laquaglia M, Ferruci J. Cytomegalovirus- and cryptosporidium-associated acalculous gangrenous cholecystitis. Am J Med 1984;76:1118–1122
Dolmatch BL, Laing FC, Federle MP, Jeffrey RB, Cello J. AID-Srelated cholangitis: radiological findings in nine patients. Radiology 1987:163:313–316
Comer GM. Gastrointestinal and nutritional manifestations of AIDS. New York: Raven Press, 1991;7:119–140
Naveh Y, Mendelsohn H, Spira G, Auslander L, Mandel H, Berant M. Primary sclerosing cholangitis associated with immunodeficiency. Am J Dis Child 1983;137:114–117
Davis J, Heyman M, Ferrell L, Kerner J, Kerlan R, Thaler M. Sclerosing cholangitis associated with chrome cryptosporidiosis in a child with a congenital immunodeficiency disorder. Am J Gastroenterol 1987;82:1196–1202
Record CO, Eddleston ALWF, Shilkin KB. Intrahepatic sclerosing cholangitis associated with a familial immunodeficiency syndrome. Lancet 1973;2:18–20
Thomas T, Ochs HD, Wedgwood RJ. Liver disease and immunodeficiency syndromes. Lancet 1974;2:311
Ament ME, Ochs HD, Davis SD. Structure and function of the gastrointestinal tract in primary immunodeficiency syndromes: a study of 39 patients. Medicine 1973:52:227–248
Agha FP, Nostrant TT, Abrams GD, Mazanee M, VanMoll L, Gumucio JJ. Cytomegalovirus cholangitis in a homosexual man with acquired immune deficiency syndrome. Am J Gastroenterol 1986:81:1068–1071
Kavin H, Jonas R, Chowwdhury L, Kabins S. Acalcalous cholecystitis and cytomegalovirus infection in the acquired immunodeficiency syndrome. Ann Int Med 1986;104:53–54
Yana C, Frija J, Cyna-Gorse F, et al. Radiological appearance of noncalculous gallbladder and bile inflammation in AIDS. J Radiol 1989:70:411–414
Cello J. Acquired immunodeficiency syndrome cholangiopathy: spectrum of disease. Am J Med 1989;86:539–546
Teixidor H, Godwin T, Ramirez E. Cryptosporidiosis of the biliary tract in AIDS. Radiology 1991;1807:51–56
Hinant K, Rotterdam H. Acalculous cholecystitis in the acquired immunodeficiency syndrome. In: Rotterdam H, Racz P, Greco MA, Cacherell CJ, eds. Progress in AIDS pathology, vol. 2. New York: Field and Wood, 1990:151–162
Aaron J, Wynter C, Kirton O, Simko V. Cytomegalovirus associated with acalculous cholecystitis in a patient with acquired immune deficiency syndrome. Am J Gastroenterol 1988;83:879–881
Forbes A, Blanshard C, Gazzard B. Natural history of AIDS related sclerosing cholangitis: a study of 20 cases. Gut 1993;34:116–121
Author information
Authors and Affiliations
Additional information
An editorial commentary on this article follows on pp. 423–424.
Rights and permissions
About this article
Cite this article
Farman, J., Brunetti, J., Baer, J.W. et al. AIDS-related cholangiopancreatographic changes. Abdom Imaging 19, 417–422 (1994). https://doi.org/10.1007/BF00206928
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00206928