Skip to main content
SpringerLink
Log in

Cytostatics — induced tubular toxicity

  • Guest Lectures, “Gessellschaft für Nephrologie”, 24th Congress
  • Published:
The clinical investigator Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bellin SL, Selim M (1988) Cisplatin-induced hypomagnesemia with seizures: a case report and review of the literature. Gynecol Oncol 30:104–113

    Google Scholar 

  2. Bitran JD, Desser RK, Billings AA, Kozloff AF, Shapiro CM (1982) Acute nephrotoxicity following cis-dichlorodiammine-platinum. Cancer 49:1784–1788

    Google Scholar 

  3. Brandis, M (1989) Nephrologische Aspekte bei Tumorerkrankungen im Kindesalter. Monatsschr für Kinderheilkd 137:643–648

    Google Scholar 

  4. Buamah PK, Howell A, Whitby H, Harpur ES, Goscher A (1982) Assessment of renal function during high-dose cis-platinum therapy in patients with ovarian carcinoma. Cancer Chemother Pharmacol 8:281–284

    Google Scholar 

  5. Caron HN, Abeling N, Kraker J de, Gennip A van, Voute PA (1989) Hyperaminoaciduria, a functional index of ifosfamide-induced renal tubular dysfunction. Med Pediatr Oncol 17:326

    Google Scholar 

  6. Daley-Yates PT, McBrien DC (1985) The renal fractinal clearance of platinum antitumor compounds in relation to nephrotoxicity. Biochem Pharmacol 34:1423–1428

    Google Scholar 

  7. Daugaard G, Abildgaard ADJ (1989) Cisplatin nephrotoxicity. Cancer Chemother Pharmacol 25:1

    Google Scholar 

  8. Dobyan DC (1985)Long-term consequences of cis-platinum-induced renal injury: a structural and functional study. Anat Rex 212:239–245

    Google Scholar 

  9. DeFronzo RA, Abeloff M,, Braine H, Humphrey RL, Davis PJ (1974) Renal dysfunction after treatment with isophosphamide. Cancer Chemother 58:375–382

    Google Scholar 

  10. Fillastre JP, Viotte G, Morin JP, Moulin B (1988) Nephrotoxicity of antitumor agents. Adv Nephrol 17:175–218

    Google Scholar 

  11. Garnick MB, Mayer RJ, Abelson HT (1988) Acute renal failure associated with cancer treatment. In: Brenner BM, Lazarus JM (eds) Acute renal failure, 2nd edn. Churchill Livingstone, New York, pp 621–657

    Google Scholar 

  12. Goldstein RS, Mayor GH (1983) Minireview. The nephrotoxicity of cisplatin. Life Sci 32:685–690

    Google Scholar 

  13. Gomez Campdera FJ, Gonzalez P, Carillo A, Estelles MC, Rengel M (1986) Cisplatin nepthrotoxicity: symptomatic hypomagnesemia and renal failure. Int J Ped Nephrol 7:151

    Google Scholar 

  14. Goren MP, Wright RK, Horowitz ME (1986) Increased levels of urinary adenosine deaminase binding protein in children treated with cisplatin or methotrexate. Clin Chem Acta 160:157

    Google Scholar 

  15. Goren MP, Wright RK, Horowitz ME, Pratt CB (1987) Ifosfamide-induced subclinical tubular nephrotoxicity despite mesna. Cancer Treat Rep 71:127–130

    Google Scholar 

  16. Hardaker WT Jr, Stone RA, McCoy R (1974) Platinum nephrotoxicity. Cancer 34:1030–1032

    Google Scholar 

  17. Heney D, Lewis IJ, Bailey CC (1989) Acute ifosfamide-induced tubular toxicity. Lancet II:103–104

    Google Scholar 

  18. Hill JB, Blachley JD, Trotter M (1978) Hypomagnesemia, hypocalcemia, and hypokalemia with cis-platinum treatment. Clin Res 26:780 (abstract)

    Google Scholar 

  19. Husband DJ, Watkin SW (1988) Fatal hypokalemia associated with ifosfamide/mesna chemotherapy. Lancet I:1116

    Google Scholar 

  20. Jacobs C, Sikic BI, Halsey J, Lum B, Goshland M, Kaubisch S, Coleman CN (1989) Protection of cis-platinum nephrotoxicity with probenecid: a phase I trial. Proc Am Soc Clin Oncol 8:78

    Google Scholar 

  21. Jaffe N, Keifer R, Robertson, Cangir A, Wang A (1987) Renal toxicity with cumulative doses of cis-diamminedichloro-platinum-II in pedatric patients with osteosarcoma. Cancer 59:1577–1581

    Google Scholar 

  22. Kreusser W, Herrmann R, Tschope W, Ritz E (1982) Nephrological complications of cancer therapy. Contrib Nephrol 33:223–231

    Google Scholar 

  23. Lammers PJ, White L, Ettinger LJ (1984) cis-Platinum-induced renal sodium wasting. Med Ped Oncol 12:343–346

    Google Scholar 

  24. Link DA, Fosburg MT, Ingelfinger JR, Tobias JS, Jaffe N (1976) Renal toxicity of high-dose methotrexate. Pediatr. Res 10:455 (abstract)

    Google Scholar 

  25. Moncrieff M, Foot A (1989) Fanconi syndrome after ifosfamide. Cancer Chemother Pharmacol 23:121–122

    Google Scholar 

  26. Ries F, Klastersky J (1986) Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatinum toxicity. Am J Kidnea Dis 8:368–379

    Google Scholar 

  27. Rieselbach RE, Garnick MB (1988) Renal disease induced by antineoplastic agents. In: Schrier RW, Gottschalk CW(eds) Diseases of the kidney, vol II, 4th edn. Little, Brown & Co, Boston, pp 1275–1299

    Google Scholar 

  28. Safirstein R, Winston J, Goldstein M, Moel D, Dikman S, Gottenplan J (1987) Cisplatin nephrotoxicity: insights into mechanism. Int J Androl 25:325–346

    Google Scholar 

  29. Schilsky RL, Anderson T (1979) Hypomagesemia and renal magnesium wasting in patients recieving cisplatin. Ann Intern Med 90:929–931

    Google Scholar 

  30. Skinner R, Person ADJ, Price L, Cunningham K, Craft AW (1989) Hypophosphatemic ricketts after ifosfamide treatment in children. Br Med J 298:1560–1561

    Google Scholar 

  31. Skinner R, Pearson ADJ, Price L, Coulthard MG, Craft AW (1990) Nephrotoxicity after ifosfamide. Arch Dis Child 65:732–738

    Google Scholar 

  32. Skinner R, Pearson ADJ, Coulthard MG, Skillen AW Hodson AW, Goldfinch ME, Gibb I, Craft AW (1991) Assessment of chemotherapy-associated nephrotoxicity in children with cancer. Cancer Chemother Pharmacol 28:81–92

    Google Scholar 

  33. Sleijfer DT, Smit EF, Meijer S, Mulder NH, Postmus PE (1989) Acute and cumulative effects of carboplatin on renal function. Br J Cancer 60:116–120

    Google Scholar 

  34. Smeitink J, Verreussel M, Schroder C, Lippens R(1988) Nephrotoxicity associated with ifosfamide. Eur J Pediatr 148:164–166

    Google Scholar 

  35. Womer RB, Pritchard J, Barratt TM (1985) Renal toxicity of cisplatin in children. J Pediatr 106:659–663

    Google Scholar 

Download references

Author information

Author notes

  1. M. Brandis (Prof)

    Present address: Universitätskinderklinik, Albert-Ludwigs-Universität, Mathildenstrasse 1, D-79104, Freiburg i.Br., Germany

Authors and Affiliations

  1. Universitätskinderklinik, Freiburg, Germany

    M. Brandis (Prof), K. v. d. Hardt, R. B. Zimmerhackl, M. Mohrmann & J. Leititis

Authors
  1. M. Brandis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. v. d. Hardt
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. B. Zimmerhackl
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. Mohrmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. J. Leititis
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Brandis, M., Hardt, K.v.d., Zimmerhackl, R.B. et al. Cytostatics — induced tubular toxicity. Clin Investig 71, 855–857 (1993). https://doi.org/10.1007/BF00190337

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00190337

Keywords

Search

Navigation