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Proteoglycans with affinity for the neuralizing factor and the vegetalizing factor (activin A homologue)

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Abstract

Proteoglycans from chicken embryos bind neuralizing and vegetalizing inducing factors. The proteoglycan-factor complexes have no inducing activity. Enzymatic cleavage of the core proteins of the proteoglycans abolishes inhibition of the inducing activity by proteoglycans. The possible significance of the formation of complexes of inducing factors with proteoglycans is discussed.

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Authors and Affiliations

  1. Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Arnimallee 22, W-1000, Berlin 33, Germany

    Hildegard Tiedemann, Jochen Born & Heinz Tiedemann

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  1. Hildegard Tiedemann
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  2. Jochen Born
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  3. Heinz Tiedemann
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Correspondence to: H. Tiedemann

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Tiedemann, H., Born, J. & Tiedemann, H. Proteoglycans with affinity for the neuralizing factor and the vegetalizing factor (activin A homologue). Roux's Arch Dev Biol 202, 316–320 (1993). https://doi.org/10.1007/BF00188730

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  • DOI: https://doi.org/10.1007/BF00188730

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