Summary
We present the case of a 57 year old man who developed a B-cell lymphoma which involved his lymph nodes, liver, spleen, bone marrow, and peripheral blood. Shortly after attaining a complete remission with chemotherapy, the patient developed profound hyperventilation with no apparent cardiac or pulmonary cause. After one month, the patient developed a 7th nerve palsy and a subsequent work-up demonstrated that he had lymphomatous meningitis. The hyperventilation resolved completely with intrathecal chemotherapy, although the patient eventually died of widely disseminated lymphoma.
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Karp, G., Nahum, K. Hyperventilation as the initial manifestation of lymphomatous meningitis. J Neuro-Oncol 13, 173–175 (1992). https://doi.org/10.1007/BF00172767
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DOI: https://doi.org/10.1007/BF00172767